PSMF1 抗体 (C-Term)
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- 抗原 See all PSMF1 抗体
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMF1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to PSMF1 (proteasome (prosome, macropain) inhibitor subunit 1 (PI31))
PSMF1 antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human PSMF1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PSMF1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.02 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PSMF1 (Proteasome (Prosome, Macropain) Inhibitor Subunit 1 (PI31) (PSMF1))
- 别名
- proteasome inhibitor subunit 1 (PSMF1 产品)
- 别名
- PI31 antibody, AW048666 antibody, BC012260 antibody, zgc:92785 antibody, proteasome inhibitor subunit 1 antibody, proteasome (prosome, macropain) inhibitor subunit 1 antibody, PSMF1 antibody, Psmf1 antibody, psmf1 antibody
- 背景
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The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a protein that inhibits the activation of the proteasome by the 11S and 19S regulators. Alternative transcript variants have been identified for this gene.
- 分子量
- 30 kDa
- 基因ID
- 9491
- UniProt
- Q92530
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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