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- 抗原 See all SOCS5 抗体
- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
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抗原表位
- N-Term
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SOCS5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 大鼠, 猪, 小鸡, 猕猴, 牛
- 交叉反应 (详细)
- Rat (100 %), Pig (100 %), Chicken (100 %), Rhesus Monkey (100 %), Bovine (100 %)
- 产品特性
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Rabbit Polyclonal antibody to SOCS5 (suppressor of cytokine signaling 5)
SOCS5 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human SOCS5. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: Molt-4 , NT2D1 , PC-3 , mouse testis
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS, 40 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Duck Tembusu Virus Utilizes miR-221-3p Expression to Facilitate Viral Replication via Targeting of Suppressor of Cytokine Signaling 5." in: Frontiers in microbiology, Vol. 11, pp. 596, (2020) (PubMed).
: "Angpt2 Induces Mesangial Cell Apoptosis through the MicroRNA-33-5p-SOCS5 Loop in Diabetic Nephropathy." in: Molecular therapy. Nucleic acids, Vol. 13, pp. 543-555, (2018) (PubMed).
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Duck Tembusu Virus Utilizes miR-221-3p Expression to Facilitate Viral Replication via Targeting of Suppressor of Cytokine Signaling 5." in: Frontiers in microbiology, Vol. 11, pp. 596, (2020) (PubMed).
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- 抗原
- SOCS5 (Suppressor of Cytokine Signaling 5 (SOCS5))
- 别名
- SOCS5 (SOCS5 产品)
- 别名
- SOCS5 antibody, cis6 antibody, cish5 antibody, cish6 antibody, socs-5 antibody, GB18949 antibody, socs5 antibody, zgc:153506 antibody, CIS6 antibody, CISH6 antibody, Cish5 antibody, SOCS-5 antibody, 1810018L08Rik antibody, mKIAA0671 antibody, RGD1564914 antibody, suppressor of cytokine signaling 5 antibody, suppressor of cytokine signaling 5a antibody, suppressor of cytokine signaling 5 L homeolog antibody, SOCS5 antibody, socs5 antibody, LOC552036 antibody, socs5a antibody, Tsp_07018 antibody, socs5.L antibody, Socs5 antibody
- 背景
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The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS) family, also known as STAT-induced STAT inhibitor (SSI) protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The specific function of this protein has not yet been determined. Two alternatively spliced transcript variants encoding an identical protein have been reported.
- 分子量
- 61 kDa
- 基因ID
- 9655
- 途径
- JAK/STAT Signaling, EGFR Signaling Pathway, Positive Regulation of Immune Effector Process
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