DUSP10 抗体 (C-Term)
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- 抗原 See all DUSP10 抗体
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DUSP10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to DUSP10 (dual specificity phosphatase 10)
DUSP10 antibody [C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human DUSP10. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product DUSP10 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- DUSP10 (Dual Specificity Phosphatase 10 (DUSP10))
- 别名
- dual specificity phosphatase 10 (DUSP10 产品)
- 别名
- DUSP10 antibody, MKP-5 antibody, MKP5 antibody, 2610306G15Rik antibody, AI158871 antibody, Mkp-5 antibody, Mkp5 antibody, dual specificity phosphatase 10 antibody, DUSP10 antibody, Dusp10 antibody
- 背景
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Dual specificity protein phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the MAPK superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of this family of dual specificity phosphatases show distinct substrate specificities for MAPKs, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product binds to and inactivates p38 and SAPK/JNK, but not MAPK/ERK. Its subcellular localization is unique, it is evenly distributed in both the cytoplasm and the nucleus. This gene is widely expressed in various tissues and organs, and its expression is elevated by stress stimuli. Three transcript variants encoding two different isoforms have been found for this gene.
- 分子量
- 53 kDa
- 基因ID
- 11221
- UniProt
- Q9Y6W6
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