MMP7 抗体 (C-Term)
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- 抗原 See all MMP7 抗体
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MMP7 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- Cow, 人, 小鼠, 大鼠
- 产品特性
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Rabbit polyclonal antibody to MMP7 (matrix metallopeptidase 7 (matrilysin, uterine))
MMP7 antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human MMP7. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product MMP7 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.45 mg/mL
- 缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signalling." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1684-1695, (2019) (PubMed).
: "The role of kinesin KIF18A in the invasion and metastasis of hepatocellular carcinoma." in: World journal of surgical oncology, Vol. 16, Issue 1, pp. 36, (2018) (PubMed).
: "Overexpression of MMP-7 Increases Collagen 1A2 in the Aging Kidney." in: Physiological reports, Vol. 1, Issue 5, (2013) (PubMed).
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FHL2 promotes tubular epithelial-to-mesenchymal transition through modulating β-catenin signalling." in: Journal of cellular and molecular medicine, Vol. 22, Issue 3, pp. 1684-1695, (2019) (PubMed).
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- 抗原
- MMP7 (Matrix Metallopeptidase 7 (Matrilysin, Uterine) (MMP7))
- 别名
- matrix metallopeptidase 7 (MMP7 产品)
- 别名
- MAT antibody, MPMM antibody, MMP-7 antibody, MPSL1 antibody, PUMP-1 antibody, matrilysin antibody, LOC727698 antibody, MMP7 antibody, Matrilysin antibody, matrix metallopeptidase 7 antibody, MMP7 antibody, Mmp7 antibody
- 背景
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Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.
Cellular Localization: Secreted , extracellular space , extracellular matrix - 分子量
- 30 kDa
- 基因ID
- 4316
- UniProt
- P09237
- 途径
- Production of Molecular Mediator of Immune Response
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