HSD11B1 抗体 (C-Term)
(1 reference)-
- 抗原 See all HSD11B1 抗体
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD11B1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人, 绵羊
- 产品特性
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Rabbit Polyclonal antibody to HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1)
HSD11B1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human HSD11B1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product HSD11B1 Primary Antibody
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anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 201-292) antibody
HSD11B1 适用: 人, 小鼠, 大鼠, 马 ELISA, IHC (p), IHC (fro), IF (cc), IF (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 适用: 人, 小鼠, 大鼠, 犬, 兔, 绵羊, Cow, 马, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C10 unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 25-292) antibodyHSD11B1 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 1-292) antibodyHSD11B1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (N-Term) antibodyHSD11B1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (AA 77-92) antibodyHSD11B1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1) (Internal Region) antibodyVerified HSD11B1 适用: 小鼠 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 40 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).
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: "Local cortisol activation is involved in EGF-induced immunosuppression." in: Dermato-endocrinology, Vol. 9, Issue 1, pp. e1412018, (2017) (PubMed).
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- 抗原
- HSD11B1 (Hydroxysteroid (11-Beta) Dehydrogenase 1 (HSD11B1))
- 别名
- hydroxysteroid 11-beta dehydrogenase 1 (HSD11B1 产品)
- 别名
- 11-DH antibody, 11-beta-HSD1 antibody, CORTRD2 antibody, HDL antibody, HSD11 antibody, HSD11B antibody, HSD11L antibody, SDR26C1 antibody, hsd11 antibody, hsd11b antibody, LRRGT00065 antibody, hydroxysteroid 11-beta dehydrogenase 1 antibody, hydroxysteroid (11-beta) dehydrogenase 1b antibody, hydroxysteroid (11-beta) dehydrogenase 1 L homeolog antibody, HSD11B1 antibody, HSD11B1b antibody, hsd11b1.L antibody, Hsd11b1 antibody
- 背景
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The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene.
Cellular Localization: Endoplasmic reticulum membrane - 分子量
- 32 kDa
- 基因ID
- 3290
- UniProt
- P28845
- 途径
- Metabolism of Steroid Hormones and Vitamin D, Steroid Hormone Biosynthesis, Regulation of Carbohydrate Metabolic Process
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