GPC1 抗体
(2 references)-
- 抗原 See all GPC1 抗体
- GPC1 (Glypican 1 (GPC1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GPC1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to Glypican 1 (glypican 1)
Glypican 1 antibody [N3C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Glypican 1. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Glypican 1 (GPC1) (AA 155-292) antibody
GPC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 342-530) antibodyGPC1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 24-131) antibodyGPC1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 12-41), (N-Term) antibodyGPC1 适用: 人 WB, IHC (p), FACS, EIA 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 301-400) antibodyGPC1 适用: 人 ELISA, IF (cc), IF (p), ICC, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 114-277) antibodyGPC1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 343-545) antibodyGPC1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (Internal Region) antibodyVerified GPC1 适用: 人 WB, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Glypican 1 (GPC1) (AA 290-420) antibodyGPC1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. FACS: 1:50-1:200. IP: 1:100-1:500. ELISA: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MDA-MB-231 , MDA-MB-231 (24 μg/ml Tunicamycin for 16hr) , U87-MG membrane extracts , U87-MG conditioned medium , Mouse brain , mouse fetal brain , A431 , MCF-7 , AsPC-1
Validation: Comparison, KO/KD, Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.58 mg/mL
- 缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma." in: Cancer medicine, Vol. 6, Issue 6, pp. 1181-1191, (2018) (PubMed).
: "α3 Chains of type V collagen regulate breast tumour growth via glypican-1." in: Nature communications, Vol. 8, pp. 14351, (2018) (PubMed).
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: "Elevated glypican-1 expression is associated with an unfavorable prognosis in pancreatic ductal adenocarcinoma." in: Cancer medicine, Vol. 6, Issue 6, pp. 1181-1191, (2018) (PubMed).
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- 抗原
- GPC1 (Glypican 1 (GPC1))
- 别名
- glypican 1 (GPC1 产品)
- 别名
- gpc1 antibody, zgc:63947 antibody, GPC1 antibody, Glypican-1 antibody, glypican antibody, AI462976 antibody, HSPG M12 antibody, HSPGM12 antibody, glypican 1b antibody, glypican 1 antibody, gpc1b antibody, GPC1 antibody, gpc1 antibody, Gpc1 antibody
- 背景
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Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation.
- 分子量
- 62 kDa
- 基因ID
- 2817
- UniProt
- P35052
- 途径
- Glycosaminoglycan Metabolic Process, Regulation of Muscle Cell Differentiation
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