ETS2 抗体 (Center)
-
- 抗原 See all ETS2 抗体
- ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
-
抗原表位
- Center
-
适用
- 人, 大鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ETS2 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)
- 产品特性
-
Rabbit Polyclonal antibody to ETS2 (v-ets erythroblastosis virus E26 oncogene homolog 2 (avian))
ETS2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human ETS2. The exact sequence is proprietary.
- 亚型
- IgG
-
-
- 应用备注
- Suggested dilution Reference ChIP assay Assay-dependent dilution ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceChIP assayAssay-dependent dilution ICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
- 说明
-
Positive Control: HeLa
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
-
Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma." in: PLoS genetics, Vol. 15, Issue 7, pp. e1008250, (2019) (PubMed).
: "Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma." in: Cancer research, Vol. 77, Issue 23, pp. 6614-6626, (2018) (PubMed).
: "Functional dissection of breast cancer risk-associated TERT promoter variants." in: Oncotarget, Vol. 8, Issue 40, pp. 67203-67217, (2017) (PubMed).
: "
-
Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma." in: PLoS genetics, Vol. 15, Issue 7, pp. e1008250, (2019) (PubMed).
-
- 抗原
- ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
- 别名
- ETS2 (ETS2 产品)
- 别名
- 0123/09 antibody, 0608/07 antibody, 0998/12 antibody, 3520 antibody, CG17077 antibody, CG8705 antibody, D-Ets-2 antibody, D-ets-2 antibody, DMPOINT1A antibody, Dmel\\CG17077 antibody, E(E2F)3D antibody, EK3-2 antibody, ETS2 antibody, EY3-1 antibody, Ets antibody, Ets2 antibody, Ets58AB antibody, Ets94F antibody, PNT-P1 antibody, PNTP1 antibody, PNTP2 antibody, POINT antibody, Pnt antibody, Pnt-P1 antibody, PntP1 antibody, PntP2 antibody, Pointed-P1 antibody, ets94F antibody, l(3)07825 antibody, l(3)j1B7 antibody, l(3)s118306 antibody, png antibody, pnt-P1 antibody, pnt-P2 antibody, pntP2 antibody, pntegfr antibody, pointed-RC antibody, ptd antibody, zgc:92106 antibody, wu:fe02h08 antibody, wu:fk74c05 antibody, AU022856 antibody, Ets-2 antibody, ETS2IT1 antibody, c-ets-2 antibody, pointed antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antibody, E26 avian leukemia oncogene 2, 3' domain antibody, ETS proto-oncogene 2, transcription factor antibody, pnt antibody, ets2 antibody, Ets2 antibody, ETS2 antibody
- 背景
-
ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]
Cellular Localization: Nucleus - 分子量
- 53 kDa
- 基因ID
- 2114
- 途径
- EGFR Signaling Pathway, Myometrial Relaxation and Contraction
-