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ETS2 抗体 (Center)

ETS2 适用: 人, 大鼠 WB, IF, IHC (p), IP, ChIP, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855845
发货至: 中国
  • 抗原 See all ETS2 抗体
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    抗原表位
    • 9
    • 7
    • 7
    • 6
    • 6
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 46
    • 10
    • 8
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    人, 大鼠
    宿主
    • 41
    • 6
    克隆类型
    • 44
    • 3
    多克隆
    标记
    • 27
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ETS2 antibody is un-conjugated
    应用范围
    • 35
    • 22
    • 16
    • 15
    • 5
    • 5
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Chromatin Immunoprecipitation (ChIP), Immunocytochemistry (ICC)
    产品特性
    Rabbit Polyclonal antibody to ETS2 (v-ets erythroblastosis virus E26 oncogene homolog 2 (avian))
    ETS2 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ETS2. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    Suggested dilution Reference ChIP assay Assay-dependent dilution ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Immunoprecipitation 1:100-1:500* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceChIP assayAssay-dependent dilution ICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Immunoprecipitation1:100-1:500* Western blot1:500-1:3000*
    说明

    Positive Control: HeLa

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS, 1 % BSA, 20 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Gluck, Glathar, Tsompana, Nowak, Garrett-Sinha, Buck, Sinha: "Molecular dissection of the oncogenic role of ETS1 in the mesenchymal subtypes of head and neck squamous cell carcinoma." in: PLoS genetics, Vol. 15, Issue 7, pp. e1008250, (2019) (PubMed).

    Yuan, Jiang, Mayakonda, Huang, Ding, Lin, Yu, Lu, Loh, Chow, Savage, Tyner, Lin, Koeffler: "Super-Enhancers Promote Transcriptional Dysregulation in Nasopharyngeal Carcinoma." in: Cancer research, Vol. 77, Issue 23, pp. 6614-6626, (2018) (PubMed).

    Helbig, Wockner, Bouendeu, Hille-Betz, McCue, French, Edwards, Pickett, Reddel, Chenevix-Trench, Dörk, Beesley: "Functional dissection of breast cancer risk-associated TERT promoter variants." in: Oncotarget, Vol. 8, Issue 40, pp. 67203-67217, (2017) (PubMed).

  • 抗原
    ETS2 (V-Ets Erythroblastosis Virus E26 Oncogene Homolog 2 (ETS2))
    别名
    ETS2 (ETS2 产品)
    别名
    0123/09 antibody, 0608/07 antibody, 0998/12 antibody, 3520 antibody, CG17077 antibody, CG8705 antibody, D-Ets-2 antibody, D-ets-2 antibody, DMPOINT1A antibody, Dmel\\CG17077 antibody, E(E2F)3D antibody, EK3-2 antibody, ETS2 antibody, EY3-1 antibody, Ets antibody, Ets2 antibody, Ets58AB antibody, Ets94F antibody, PNT-P1 antibody, PNTP1 antibody, PNTP2 antibody, POINT antibody, Pnt antibody, Pnt-P1 antibody, PntP1 antibody, PntP2 antibody, Pointed-P1 antibody, ets94F antibody, l(3)07825 antibody, l(3)j1B7 antibody, l(3)s118306 antibody, png antibody, pnt-P1 antibody, pnt-P2 antibody, pntP2 antibody, pntegfr antibody, pointed-RC antibody, ptd antibody, zgc:92106 antibody, wu:fe02h08 antibody, wu:fk74c05 antibody, AU022856 antibody, Ets-2 antibody, ETS2IT1 antibody, c-ets-2 antibody, pointed antibody, v-ets avian erythroblastosis virus E26 oncogene homolog 2 antibody, E26 avian leukemia oncogene 2, 3' domain antibody, ETS proto-oncogene 2, transcription factor antibody, pnt antibody, ets2 antibody, Ets2 antibody, ETS2 antibody
    背景
    ETS transcriptions factors, such as ETS2, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (Dwyer et al., 2007 [PubMed 17986575]).[supplied by OMIM]

    Cellular Localization: Nucleus
    分子量
    53 kDa
    基因ID
    2114
    途径
    EGFR Signaling Pathway, Myometrial Relaxation and Contraction
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