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PSME1 抗体

PSME1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855823
发货至: 中国
  • 抗原 See all PSME1 抗体
    PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
    适用
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    宿主
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    克隆类型
    • 52
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    多克隆
    标记
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    This PSME1 antibody is un-conjugated
    应用范围
    • 50
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    Western Blotting (WB)
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to PSME1 (proteasome (prosome, macropain) activator subunit 1 (PA28 alpha))
    PSME1 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PSME1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PSME1 Primary Antibody
  • 应用备注
    WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.93 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PSME1 (Proteasome (Prosome, Macropain) Activator Subunit 1 (PA28 Alpha) (PSME1))
    别名
    proteasome activator subunit 1 (PSME1 产品)
    别名
    fk89d05 antibody, wu:fk89d05 antibody, IFI5111 antibody, PA28A antibody, PA28alpha antibody, REGalpha antibody, AW413925 antibody, PA28a antibody, proteasome activator subunit 1 antibody, proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) antibody, psme1 antibody, PSME1 antibody, Psme1 antibody
    背景
    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Two transcripts encoding different isoforms have been identified.

    分子量
    29 kDa
    基因ID
    5720
    UniProt
    Q06323
    途径
    Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA
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