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GLB1 抗体

GLB1 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855812
发货至: 中国
  • 抗原 See all GLB1 抗体
    GLB1 (Galactosidase, beta 1 (GLB1))
    适用
    • 66
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    宿主
    • 62
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    克隆类型
    • 66
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    多克隆
    标记
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    This GLB1 antibody is un-conjugated
    应用范围
    • 95
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 大鼠
    产品特性
    Rabbit polyclonal antibody to beta-Gal (galactosidase, beta 1)
    beta-Gal antibody [N2C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human beta-Gal. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product GLB1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.35 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chang, Su, Chen, Chen, Chen, Hsiao: "Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis." in: Molecular cancer, Vol. 16, Issue 1, pp. 135, (2018) (PubMed).

  • 抗原
    GLB1 (Galactosidase, beta 1 (GLB1))
    别名
    galactosidase beta 1 (GLB1 产品)
    背景
    This gene encodes beta-galactosidase-1, a lysosomal enzyme that hydrolyzes the terminal beta-galactose from ganglioside substrates and other glycoconjugates. Defects in this gene are the cause of GM1-gangliosidosis and Morquio B syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Isoform 1: Lysosome , Isoform 2: Cytoplasm , perinuclear region
    分子量
    76 kDa
    基因ID
    2720
    UniProt
    P16278
    途径
    Glycosaminoglycan Metabolic Process
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