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PYGB 抗体 (C-Term)

Name: PYGB 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN2855804
Availability: OutOfStock

GPBB 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7. (PYGB 抗体 (C-Term))

WB Image Sample(30 ug whole cell lysate) A:Hep G2 , 7. (PYGB 抗体 (C-Term))

IHC-P Image GPBB antibody detects GPBB protein at cytosol on mouse fore brain by immunohistochemical analysis. (PYGB 抗体 (C-Term))

IHC

IHC-P Image GPBB antibody detects PYGB protein at cytosol on U87 xenograft by immunohistochemical analysis. (PYGB 抗体 (C-Term))

IHC

Increased GDH and GPBB in Psmc1fl/fl,CaMKIIα-Cre forebrain. (PYGB 抗体 (C-Term))

IHC

6 images

(2 references)

产品编号 ABIN2855804

发货至: 中国

Datasheet as PDF

抗原 See all PYGB (GPBB) 抗体

PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))
抗原表位
14

10

6

2

1

1

1

1

1

1
C-Term
适用
62

46

30

4

3

3

3

2

1

1

1

1

1

1

1

1

1

1

1

1
人, 小鼠
宿主
71

5
兔
Compatible Secondaries
克隆类型
71

5
多克隆
标记
28

7

7

6

3

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
This PYGB antibody is un-conjugated
应用范围
44

33

14

13

4

3

3

2

2

1

1

1

1

1
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

产品特性

Rabbit Polyclonal antibody to GPBB (phosphorylase, glycogen, brain)
GPBB antibody

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human GPBB. The exact sequence is proprietary.

亚型

IgG
anti-phosphorylase, Glycogen, Brain (GPBB) (AA 477-731) antibody
GPBB 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) (AA 544-843) antibody
GPBB 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) (AA 6-843) antibody
GPBB 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) antibody
GPBB 适用: 人, 小鼠, 大鼠 WB, IF 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) (C-Term) antibody
GPBB 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) (C-Term) antibody
GPBB 适用: 人, 兔, 猴 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) antibody
GPBB 适用: 人, 小鼠, 大鼠 WB, IHC, IF, IC 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) antibody
GPBB 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) (AA 180-229) antibody
GPBB 适用: 人, 小鼠, 兔, 绵羊, Cow, 猴 WB 宿主: 兔 Polyclonal unconjugated

anti-phosphorylase, Glycogen, Brain (GPBB) (AA 1-843) antibody
GPBB 适用: 人 WB 宿主: 兔 Polyclonal unconjugated

应用备注

Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*

说明

Positive Control: HepG2 , mouse brain

限制

仅限研究用
状态

Liquid

浓度

0.84 mg/mL

缓冲液

0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
Cooper, Pasini, Lambert, DAlessandro, Yao, Risner, Calkins: "Redistribution of metabolic resources through astrocyte networks mitigates neurodegenerative stress." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 117, Issue 31, pp. 18810-18821, (2020) (PubMed).

Geiszler, Ugun-Klusek, Lawler, Pardon, Yuchun, Bai, Daykin, Auer, Bedford: "Dynamic metabolic patterns tracking neurodegeneration and gliosis following 26S proteasome dysfunction in mouse forebrain neurons." in: Scientific reports, Vol. 8, Issue 1, pp. 4833, (2019) (PubMed).
抗原

PYGB (GPBB) (phosphorylase, Glycogen, Brain (GPBB))

别名

GPBB (GPBB 产品)

别名

GPBB antibody, GLYPHOA antibody, glycogen phosphorylase B antibody, phosphorylase, glycogen; brain antibody, brain glycogen phosphorylase antibody, phosphorylase, glycogen; brain S homeolog antibody, PYGB antibody, pygb antibody, Pygb antibody, pygb.S antibody

背景

The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers, the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP, ADP, and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation.

分子量

97 kDa

基因ID

5834

途径

Cellular Glucan Metabolic Process