IRAK3 抗体
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- 抗原 See all IRAK3 抗体
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This IRAK3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to IRAK3 (interleukin-1 receptor-associated kinase 3)
IRAK3 antibody [N1C1] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human IRAK3. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product IRAK3 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: DDDDK-tagged IRAK3-transfected 293T
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.22 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- IRAK3 (Interleukin-1 Receptor-Associated Kinase 3 (IRAK3))
- 别名
- interleukin 1 receptor associated kinase 3 (IRAK3 产品)
- 别名
- IRAK3 antibody, si:dkey-150i15.2 antibody, ASRT5 antibody, IRAKM antibody, IrakM antibody, 4833428C18Rik antibody, AI563835 antibody, IRAK-M antibody, interleukin 1 receptor associated kinase 3 antibody, interleukin-1 receptor-associated kinase 3 antibody, IRAK3 antibody, irak3 antibody, Irak3 antibody
- 背景
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This gene encodes a member of the interleukin-1 receptor-associated kinase protein family. Members of this family are essential components of the Toll/IL-R immune signal transduction pathways. This protein is primarily expressed in monocytes and macrophages and functions as a negative regulator of Toll-like receptor signaling. Mutations in this gene are associated with a susceptibility to asthma. Alternate splicing results in multiple transcript variants.
- 分子量
- 68 kDa
- 基因ID
- 11213
- UniProt
- Q9Y616
- 途径
- TLR signaling, Activation of Innate immune Response, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades
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