FPGT 抗体
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- 抗原 See all FPGT 抗体
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FPGT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit polyclonal antibody to FPGT (fucose-1-phosphate guanylyltransferase)
FPGT antibody [N2C2], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human FPGT. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product FPGT Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.74 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
- 别名
- fucose-1-phosphate guanylyltransferase (FPGT 产品)
- 别名
- DDBDRAFT_0186414 antibody, DDBDRAFT_0233144 antibody, DDB_0186414 antibody, DDB_0233144 antibody, FPGT antibody, DKFZp459M111 antibody, fpgt antibody, zgc:110694 antibody, GFPP antibody, 1700016E03Rik antibody, fucose-1-phosphate guanylyltransferase antibody, fucose-1-phosphate guanylyltransferase L homeolog antibody, fpgt antibody, FPGT antibody, fpgt.L antibody, Fpgt antibody
- 背景
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L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.
Cellular Localization: Cytoplasm - 分子量
- 67 kDa
- 基因ID
- 8790
- UniProt
- O14772
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