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FPGT 抗体

FPGT 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855758
发货至: 中国
  • 抗原 See all FPGT 抗体
    FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
    适用
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    宿主
    • 32
    • 3
    克隆类型
    • 35
    多克隆
    标记
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    This FPGT antibody is un-conjugated
    应用范围
    • 31
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit polyclonal antibody to FPGT (fucose-1-phosphate guanylyltransferase)
    FPGT antibody [N2C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human FPGT. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product FPGT Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Raji

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.74 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    FPGT (Fucose-1-Phosphate Guanylyltransferase (FPGT))
    别名
    fucose-1-phosphate guanylyltransferase (FPGT 产品)
    别名
    DDBDRAFT_0186414 antibody, DDBDRAFT_0233144 antibody, DDB_0186414 antibody, DDB_0233144 antibody, FPGT antibody, DKFZp459M111 antibody, fpgt antibody, zgc:110694 antibody, GFPP antibody, 1700016E03Rik antibody, fucose-1-phosphate guanylyltransferase antibody, fucose-1-phosphate guanylyltransferase L homeolog antibody, fpgt antibody, FPGT antibody, fpgt.L antibody, Fpgt antibody
    背景
    L-fucose is a key sugar in glycoproteins and other complex carbohydrates since it may be involved in many of the functional roles of these macromolecules, such as in cell-cell recognition. The fucosyl donor for these fucosylated oligosaccharides is GDP-beta-L-fucose. There are two alternate pathways for the biosynthesis of GDP-fucose, the major pathway converts GDP-alpha-D-mannose to GDP-beta-L-fucose. The protein encoded by this gene participates in an alternate pathway that is present in certain mammalian tissues, such as liver and kidney, and appears to function as a salvage pathway to reutilize L-fucose arising from the turnover of glycoproteins and glycolipids. This pathway involves the phosphorylation of L-fucose to form beta-L-fucose-1-phosphate, and then condensation of the beta-L-fucose-1-phosphate with GTP by fucose-1-phosphate guanylyltransferase to form GDP-beta-L-fucose.

    Cellular Localization: Cytoplasm
    分子量
    67 kDa
    基因ID
    8790
    UniProt
    O14772
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