RFC4 抗体
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- 抗原 See all RFC4 抗体
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RFC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to RFC4 (replication factor C (activator 1) 4, 37 kDa)
RFC4 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human RFC4. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product RFC4 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse liver , 293T , A431 , HeLa , HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.62 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- RFC4 (Replication Factor C (Activator 1) 4, 37kDa (RFC4))
- 别名
- replication factor C subunit 4 (RFC4 产品)
- 别名
- 44.t00003 antibody, 21.m03053 antibody, rfc4 antibody, A1 antibody, AI894123 antibody, AU040575 antibody, RFC37 antibody, rfc2 antibody, replication factor C subunit 4 antibody, Replication factor C subunit 4 antibody, replication factor C (activator 1) 4 antibody, replication factor C subunit 4 L homeolog antibody, PFL2005w antibody, EHI_167150 antibody, TP03_0432 antibody, Tb11.01.1310 antibody, BBOV_IV002210 antibody, rfc4 antibody, rfc-4 antibody, Rfc4 antibody, RFC4 antibody, rfc4.L antibody
- 背景
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The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC). RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Cellular Localization: Nucleus - 分子量
- 40 kDa
- 基因ID
- 5984
- UniProt
- P35249
- 途径
- Telomere Maintenance, DNA Damage Repair, DNA Replication, Synthesis of DNA
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