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- 抗原 See all HSD17B4 抗体
- HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HSD17B4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 人, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to HSD17B4 (hydroxysteroid (17-beta) dehydrogenase 4)
HSD17B4 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human HSD17B4. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Rat heart
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).
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Developing antineoplastic agents that target peroxisomal enzymes: cytisine-linked isoflavonoids as inhibitors of hydroxysteroid 17-beta-dehydrogenase-4 (HSD17B4)." in: Organic & biomolecular chemistry, Vol. 15, Issue 36, pp. 7623-7629, (2018) (PubMed).
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- 抗原
- HSD17B4 (Hydroxysteroid (17-Beta) Dehydrogenase 4 (HSD17B4))
- 别名
- hydroxysteroid 17-beta dehydrogenase 4 (HSD17B4 产品)
- 别名
- zgc:55545 antibody, zgc:77300 antibody, CG3415 antibody, DmMFE-2 antibody, Dmel\\CG3415 antibody, MFE-2 antibody, DBP antibody, MPF-2 antibody, PRLTS1 antibody, SDR8C1 antibody, 17-beta-HSD antibody, 17[b]-HSD antibody, 4 antibody, MFP2 antibody, Mfp-2 antibody, perMFE-2 antibody, hydroxysteroid (17-beta) dehydrogenase 4 antibody, hydroxysteroid 17-beta dehydrogenase 4 antibody, peroxisomal Multifunctional enzyme type 2 antibody, hsd17b4 antibody, HSD17B4 antibody, Mfe2 antibody, Hsd17b4 antibody
- 背景
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The protein encoded by this gene is a bifunctional enzyme that is involved in the peroxisomal beta-oxidation pathway for fatty acids. It also acts as a catalyst for the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids. Defects in this gene that affect the peroxisomal fatty acid beta-oxidation activity are a cause of D-bifunctional protein deficiency (DBPD). An apparent pseudogene of this gene is present on chromosome 8.
Cellular Localization: Peroxisome - 分子量
- 80 kDa
- 基因ID
- 3295
- UniProt
- P51659
- 途径
- Monocarboxylic Acid Catabolic Process
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