L3MBTL1 抗体 (Center)
(1 reference)-
- 抗原 See all L3MBTL1 抗体
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
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抗原表位
- Center
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This L3MBTL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 小鼠
- 交叉反应 （详细）
- mouse (88 %)
- 产品特性
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Rabbit polyclonal antibody to L3MBTL (l(3)mbt-like (Drosophila))
L3MBTL antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human L3MBTL. The exact sequence is proprietary.
- 亚型
- IgG
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anti-L(3)mbt-Like 1 (L3MBTL1) (AA 1-772) antibody
L3MBTL1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 82-298) antibodyL3MBTL1 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 513-752) antibodyL3MBTL1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 451-485) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal RB53645 unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 442-491) antibodyL3MBTL1 适用: 人, 小鼠, 犬, 大鼠, 兔 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 221-270) antibodyL3MBTL1 适用: 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (N-Term) antibodyL3MBTL1 适用: 人, 豚鼠, 猴 WB 宿主: 兔 Polyclonal unconjugated
anti-L(3)mbt-Like 1 (L3MBTL1) (AA 144-193) antibodyL3MBTL1 适用: 人, 豚鼠, 兔, 马, Cow WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
- 说明
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Positive Control: HeLaS3 , human L3MBTL-transfected 293T
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C
- 储存方法
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control." in: Nature neuroscience, Vol. 22, Issue 6, pp. 875-886, (2019) (PubMed).
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: "L3MBTL1 regulates ALS/FTD-associated proteotoxicity and quality control." in: Nature neuroscience, Vol. 22, Issue 6, pp. 875-886, (2019) (PubMed).
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- 抗原
- L3MBTL1 (L(3)mbt-Like 1 (L3MBTL1))
- 别名
- L3MBTL (L3MBTL1 产品)
- 别名
- C630004G01 antibody, L3mbtl antibody, mKIAA0681 antibody, H-L(3)MBT antibody, L3MBTL antibody, ZC2HC3 antibody, dJ138B7.3 antibody, RGD1307316 antibody, l(3)mbt-like (Drosophila) antibody, L3MBTL1, histone methyl-lysine binding protein antibody, l(3)mbt-like 1 (Drosophila) antibody, L3mbtl1 antibody, L3MBTL1 antibody
- 背景
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This gene encodes the homolog of a protein identified in Drosophila as a suppressor of malignant transformation of neuroblasts and ganglion-mother cells in the optic centers of the brain. This gene product is localized to condensed chromosomes in mitotic cells. Overexpression of this gene in a glioma cell line results in improper nuclear segregation and cytokinesis producing multinucleated cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Cellular Localization: Nucleus - 分子量
- 84 kDa
- 基因ID
- 26013
- 途径
- Chromatin Binding
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