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FGFRL1 抗体

FGFRL1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855700
发货至: 中国
  • 抗原 See all FGFRL1 抗体
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    适用
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    宿主
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    多克隆
    标记
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    This FGFRL1 antibody is un-conjugated
    应用范围
    • 42
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    产品特性
    Rabbit polyclonal antibody to FGFR-5 (fibroblast growth factor receptor-like 1)
    FGFR-5 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human FGFR5. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product FGFRL1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: FGFRL1-transfected 293T , HepG2 membrane extract

    Validation: Orthogonal, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    2.42 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    FGFRL1 (Fibroblast Growth Factor Receptor-Like 1 (FGFRL1))
    别名
    fibroblast growth factor receptor like 1 (FGFRL1 产品)
    别名
    fgfrl1 antibody, zgc:64084 antibody, FGFR5 antibody, FGFR5beta antibody, FGFR5gamma antibody, Fgfr5 antibody, FHFR antibody, XFGFRL1 antibody, Xndk antibody, fgfrl1-a antibody, fgfrl1-b antibody, ndk antibody, im:7154242 antibody, fibroblast growth factor receptor like 1a antibody, fibroblast growth factor receptor-like 1 antibody, fibroblast growth factor receptor like 1 antibody, fibroblast growth factor receptor like 1 L homeolog antibody, fibroblast growth factor receptor like 1b antibody, fgfrl1a antibody, Fgfrl1 antibody, FGFRL1 antibody, fgfrl1.L antibody, fgfrl1b antibody
    背景
    The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    55 kDa
    基因ID
    53834
    UniProt
    Q8N441
    途径
    RTK signaling
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