BACE1 抗体
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- 抗原 See all BACE1 抗体
- BACE1 (Beta-secretase 1 (BACE1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BACE1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to BACE1 (beta-site APP-cleaving enzyme 1)
BACE1 antibody [N1C2] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human BACE1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product BACE1 Primary Antibody
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- 应用备注
- WB: 1:1000. IHC-P: 1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.91 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- BACE1 (Beta-secretase 1 (BACE1))
- 别名
- beta-secretase 1 (BACE1 产品)
- 别名
- ASP2 antibody, BACE antibody, HSPC104 antibody, C76936 antibody, Bace antibody, MGC145931 antibody, BACE1 antibody, zgc:77409 antibody, beta-secretase 1 antibody, beta-site APP cleaving enzyme 1 antibody, beta-site APP-cleaving enzyme 1 antibody, BACE1 antibody, Bace1 antibody, bace1 antibody
- 背景
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Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Four transcript variants encoding different isoforms have been described for this gene.
Cellular Localization: Membrane - 分子量
- 56 kDa
- 基因ID
- 23621
- UniProt
- P56817
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