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Seladin 1 抗体

DHCR24 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855685
发货至: 中国
  • 抗原 See all Seladin 1 (DHCR24) 抗体
    Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
    适用
    • 43
    • 36
    • 27
    • 4
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    • 3
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    • 1
    • 1
    宿主
    • 41
    • 2
    克隆类型
    • 43
    多克隆
    标记
    • 17
    • 2
    • 2
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    • 2
    • 2
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
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    This Seladin 1 antibody is un-conjugated
    应用范围
    • 31
    • 13
    • 13
    • 5
    • 3
    • 3
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Seladin 1 (24-dehydrocholesterol reductase)
    Seladin 1 antibody [N1C2]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Seladin 1. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.47 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Seladin 1 (DHCR24) (24-Dehydrocholesterol Reductase (DHCR24))
    别名
    24-dehydrocholesterol reductase (DHCR24 产品)
    别名
    MGC82737 antibody, zgc:101638 antibody, DCE antibody, Nbla03646 antibody, SELADIN1 antibody, seladin-1 antibody, 2310076D10Rik antibody, 5830417J06Rik antibody, mKIAA0018 antibody, 24-dehydrocholesterol reductase antibody, 24-dehydrocholesterol reductase S homeolog antibody, delta(24)-sterol reductase antibody, DHCR24 antibody, dhcr24.S antibody, dhcr24 antibody, LOC5575872 antibody, CpipJ_CPIJ000670 antibody, Dhcr24 antibody
    背景
    This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells.

    Cellular Localization: Endoplasmic reticulum membrane , Golgi apparatus membrane
    分子量
    60 kDa
    基因ID
    1718
    UniProt
    Q15392
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