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- 抗原 See all EPAS1 抗体
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EPAS1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)
- 交叉反应
- 人, 斑马鱼
- 产品特性
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Rabbit Polyclonal antibody to HIF2 alpha (endothelial PAS domain protein 1)
HIF2 alpha antibody [N1N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human HIF2 alpha. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product EPAS1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HepG2 (1% O2 treatment for 24hr)
Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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Integration of CNS survival and differentiation by HIF2α." in: Cell death and differentiation, Vol. 18, Issue 11, pp. 1757-70, (2012) (PubMed).
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Integration of CNS survival and differentiation by HIF2α." in: Cell death and differentiation, Vol. 18, Issue 11, pp. 1757-70, (2012) (PubMed).
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- 抗原
- EPAS1 (Endothelial PAS Domain Protein 1 (EPAS1))
- 别名
- endothelial PAS domain protein 1 (EPAS1 产品)
- 别名
- EPAS1 antibody, ECYT4 antibody, HIF2A antibody, HLF antibody, MOP2 antibody, PASD2 antibody, bHLHe73 antibody, HIF-2alpha antibody, HRF antibody, Hif2a antibody, bhlhe73 antibody, ecyt4 antibody, hif2 antibody, hif2a antibody, hif2alpha antibody, hlf antibody, mop2 antibody, pasd2 antibody, EPAS antibody, EPAS-1 antibody, endothelial PAS domain protein 1 antibody, endothelial PAS domain protein 1 L homeolog antibody, EPAS1 antibody, epas1 antibody, Epas1 antibody, epas1.L antibody
- 背景
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This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4.
Cellular Localization: Nucleus - 分子量
- 96 kDa
- 基因ID
- 2034
- UniProt
- Q99814
- 途径
- Signaling Events mediated by VEGFR1 and VEGFR2, Warburg Effect
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