NAB2 抗体
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- 抗原 See all NAB2 抗体
- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NAB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to NAB2 (NGFI-A binding protein 2 (EGR1 binding protein 2))
NAB2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human NAB2. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- NAB2 (NGFI-A Binding Protein 2 (EGR1 Binding Protein 2) (NAB2))
- 别名
- NGFI-A binding protein 2 (NAB2 产品)
- 别名
- mader antibody, AI451907 antibody, MADER antibody, NGFI-A binding protein 2 (EGR1 binding protein 2) antibody, Ngfi-A binding protein 2 antibody, NGFI-A binding protein 2 antibody, nab2 antibody, Nab2 antibody, NAB2 antibody
- 背景
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This gene encodes a member of the family of NGFI-A binding (NAB) proteins, which function in the nucleus to repress transcription induced by some members of the EGR (early growth response) family of transactivators. NAB proteins can homo- or hetero-multimerize with other EGR or NAB proteins through a conserved N-terminal domain, and repress transcription through two partially redundant C-terminal domains. Transcriptional repression by the encoded protein is mediated in part by interactions with the nucleosome remodeling and deactylase (NuRD) complex. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Cellular Localization: Nucleus (By similarity) - 分子量
- 57 kDa
- 基因ID
- 4665
- UniProt
- Q15742
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