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- 抗原 See all Calpain 5 (CAPN5) 抗体
- Calpain 5 (CAPN5)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Calpain 5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit polyclonal antibody to Calpain-5 (calpain 5)
Calpain-5 antibody [N1C1] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Calpain 5. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: mouse uterus , RMS-13
Validation: Orthogonal, Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.39 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay." in: Cold Spring Harbor molecular case studies, Vol. 4, Issue 3, (2019) (PubMed).
: "Calpain-5 Expression in the Retina Localizes to Photoreceptor Synapses." in: Investigative ophthalmology & visual science, Vol. 57, Issue 6, pp. 2509-21, (2016) (PubMed).
: "
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A novel de novo CAPN5 mutation in a patient with inflammatory vitreoretinopathy, hearing loss, and developmental delay." in: Cold Spring Harbor molecular case studies, Vol. 4, Issue 3, (2019) (PubMed).
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- 抗原
- Calpain 5 (CAPN5)
- 别名
- calpain 5 (CAPN5 产品)
- 别名
- HTRA3 antibody, nCL-3 antibody, Htra3 antibody, capn5 antibody, MGC53448 antibody, MGC89353 antibody, CAPN5 antibody, zgc:153446 antibody, calpain 5 antibody, calpain 5 L homeolog antibody, calpain 5a antibody, calpain 6 antibody, CAPN5 antibody, Capn5 antibody, capn5.L antibody, capn5 antibody, capn5a antibody, Bm1_30735 antibody, Bm1_30740 antibody, CAPN6 antibody, LOAG_10085 antibody
- 背景
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Calpains are calcium-dependent cysteine proteases involved in signal transduction in a variety of cellular processes. A functional calpain protein consists of an invariant small subunit and 1 of a family of large subunits. CAPN5 is one of the large subunits. Unlike some of the calpains, CAPN5 and CAPN6 lack a calmodulin-like domain IV. Because of the significant similarity to Caenorhabditis elegans sex determination gene tra-3, CAPN5 is also called as HTRA3.
- 分子量
- 73 kDa
- 基因ID
- 726
- UniProt
- O15484
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