BIN1 抗体
(1 reference)-
- 抗原 See all BIN1 抗体
- BIN1 (Bridging Integrator 1 (BIN1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BIN1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to BIN1 (bridging integrator 1)
BIN1 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human BIN1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product BIN1 Primary Antibody
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anti-Bridging Integrator 1 (BIN1) antibody
BIN1 适用: 人, 大鼠 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 230-409) antibodyBIN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 189-398) antibodyBIN1 适用: 人 WB, ELISA, FACS 宿主: 小鼠 Monoclonal 3B6A4 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 小鼠 WB, ELISA, IHC, IP, FACS 宿主: 小鼠 Monoclonal 99D unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 小鼠 WB, ELISA, IHC, IP 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 414-593) antibodyBIN1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 1-482) antibodyBIN1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 355-454) antibodyBIN1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2C7 unconjugated
anti-Bridging Integrator 1 (BIN1) antibodyBIN1 适用: 人, 小鼠 WB, ELISA, IP 宿主: 小鼠 Monoclonal 99F unconjugated
anti-Bridging Integrator 1 (BIN1) (AA 360-389) antibodyBIN1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Validation: Comparison
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 2.35 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis." in: Nature cell biology, Vol. 20, Issue 9, pp. 1023-1031, (2019) (PubMed).
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: "FBP17 and CIP4 recruit SHIP2 and lamellipodin to prime the plasma membrane for fast endophilin-mediated endocytosis." in: Nature cell biology, Vol. 20, Issue 9, pp. 1023-1031, (2019) (PubMed).
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- 抗原
- BIN1 (Bridging Integrator 1 (BIN1))
- 别名
- bridging integrator 1 (BIN1 产品)
- 别名
- bin1 antibody, MGC53185 antibody, amph2 antibody, amphl antibody, sh3p9 antibody, MGC76187 antibody, cb57 antibody, zgc:86701 antibody, BIN1 antibody, AMPH2 antibody, AMPHL antibody, SH3P9 antibody, ALP-1 antibody, Amphl antibody, BRAMP-2 antibody, bridging integrator 1 antibody, bridging integrator 1 S homeolog antibody, bridging integrator 1b antibody, BIN1 antibody, bin1.S antibody, bin1 antibody, bin1b antibody, Bin1 antibody
- 背景
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This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynanim, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described.
Cellular Localization: Isoform BIN1: Nucleus , Isoform IIA: Cytoplasm - 分子量
- 65 kDa
- 基因ID
- 274
- UniProt
- O00499
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