TFAM 抗体
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- 抗原 See all TFAM 抗体
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TFAM antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to mtTFA (transcription factor A, mitochondrial)
mtTFA antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human mtTFA. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product TFAM Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , A431 , HeLa , HepG2
Validation: KO/KD, Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1.23 mg/mL
- 缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- TFAM (Transcription Factor A, Mitochondrial (TFAM))
- 别名
- transcription factor A, mitochondrial (TFAM 产品)
- 别名
- tcf6 antibody, mttf1 antibody, mttfa antibody, tcf6l1 antibody, tcf6l2 antibody, tcf6l3 antibody, mttfa-A antibody, xl-mtTFA antibody, MGC153358 antibody, zgc:153358 antibody, MTTF1 antibody, MTTFA antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, AI661103 antibody, Hmgts antibody, mtTFA antibody, tsHMG antibody, Mttfa antibody, transcription factor A, mitochondrial antibody, transcription factor A, mitochondrial L homeolog antibody, TFAM antibody, tfam.L antibody, tfam antibody, Tfam antibody
- 背景
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This gene encodes a mitochondrial transcription factor that is a key activator of mitochondrial transcription as well as a participant in mitochondrial genome replication. Studies in mice have demonstrated that this gene product is required to regulate the mitochondrial genome copy number and is essential for embryonic development. A mouse model for Kearns-Sayre syndrome was produced when expression of this gene was eliminated by targeted disruption in heart and muscle cells.
Cellular Localization: Mitochondrion - 分子量
- 29 kDa
- 基因ID
- 7019
- UniProt
- Q00059
- 途径
- Chromatin Binding
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