ACTN2 抗体
(1 reference)-
- 抗原 See all ACTN2 抗体
- ACTN2 (Actinin, alpha 2 (ACTN2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ACTN2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 特异性
- Based on sequence homology, this antibody may cross-react with other Actinin family members.
- 交叉反应
- 人, 小鼠, Pig, 大鼠, 斑马鱼
- 产品特性
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Rabbit Polyclonal antibody to alpha Actinin 2 (actinin, alpha 2)
alpha Actinin 2 antibody [N1N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human alpha Actinin 2. The exact sequence is proprietary.
- 亚型
- IgG
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anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibody
ACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3293 unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 WB, IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3292 unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 1-254) antibodyACTN2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 557-692) antibodyACTN2 适用: 人 IHC, StM 宿主: 小鼠 Monoclonal ACTN2-3291 unconjugated
anti-Actinin, alpha 2 (ACTN2) (N-Term) antibodyACTN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) antibodyACTN2 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 11-347) antibodyACTN2 适用: 人, 小鼠 WB, IHC, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (AA 1-250) antibodyACTN2 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (C-Term) antibodyACTN2 适用: 人, 小鼠, 大鼠, 犬 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Actinin, alpha 2 (ACTN2) (C-Term) antibodyACTN2 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.18 mg/mL
- 缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training." in: PeerJ, Vol. 6, pp. e5338, (2018) (PubMed).
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: "Skeletal muscle mitochondrial volume and myozenin-1 protein differences exist between high versus low anabolic responders to resistance training." in: PeerJ, Vol. 6, pp. e5338, (2018) (PubMed).
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- 抗原
- ACTN2 (Actinin, alpha 2 (ACTN2))
- 别名
- actinin alpha 2 (ACTN2 产品)
- 别名
- MGC89234 antibody, ACTN2 antibody, 1110008F24Rik antibody, CMD1AA antibody, wu:fd44c03 antibody, zgc:123223 antibody, actinin alpha 2 antibody, actinin, alpha 2b antibody, actinin alpha 2 S homeolog antibody, actn2 antibody, ACTN2 antibody, Actn2 antibody, actn2b antibody, actn2.S antibody
- 背景
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Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles.
Cellular Localization: Cytoplasm , myofibril , sarcomere , Z-disk - 分子量
- 104 kDa
- 基因ID
- 88
- UniProt
- P35609
- 途径
- Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Negative Regulation of Transporter Activity
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