TXNRD1 抗体
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- 抗原 See all TXNRD1 抗体
- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TXNRD1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit polyclonal antibody to TrxR1 (thioredoxin reductase 1)
TrxR1 antibody [N1N3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human TrxR1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product TXNRD1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- TXNRD1 (Thioredoxin Reductase 1 (TXNRD1))
- 别名
- thioredoxin reductase 1 (TXNRD1 产品)
- 别名
- TrxR1 antibody, cb682 antibody, fb83a08 antibody, wu:fb83a08 antibody, GB14972 antibody, MGC85342 antibody, NADPH-dependent thioredoxin reductase C antibody, T32G6.20 antibody, T32G6_20 antibody, GRIM-12 antibody, TR antibody, TR1 antibody, TRXR1 antibody, TXNR antibody, Tr antibody, thioredoxin reductase 1 antibody, thioredoxin reductase 1 L homeolog antibody, NADPH-dependent thioredoxin reductase C antibody, ThioRedoXin Reductase antibody, TXNRD1 antibody, txnrd1 antibody, Trxr-1 antibody, txnrd1.L antibody, NTRC antibody, trxr-1 antibody, Txnrd1 antibody
- 背景
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This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms.
Cellular Localization: Cytoplasm , Isoform 4: Cytoplasm , Nucleus , Isoform 5: Cytoplasm - 分子量
- 71 kDa
- 基因ID
- 7296
- UniProt
- Q16881
- 途径
- Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Cell RedoxHomeostasis
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