LIG3 抗体 (C-Term)
(1 reference)-
- 抗原 See all LIG3 抗体
- LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIG3 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- Hamster, 人
- 产品特性
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Rabbit Polyclonal antibody to DNA ligase III (ligase III, DNA, ATP-dependent)
DNA ligase III antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human DNA ligase III. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product LIG3 Primary Antibody
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anti-Ligase III, DNA, ATP-Dependent (LIG3) (AA 730-1009) antibody
LIG3 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) antibodyLIG3 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) (AA 809-928) antibodyLIG3 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) (Internal Region) antibodyLIG3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) antibodyKO Validated LIG3 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) (Internal Region) antibodyLIG3 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) (AA 823-922) antibodyLIG3 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) (AA 220-269) antibodyLIG3 适用: 人, 小鼠, 大鼠, 马, 兔, 豚鼠, Cow, Bat WB 宿主: 兔 Polyclonal unconjugated
anti-Ligase III, DNA, ATP-Dependent (LIG3) (AA 930-979) antibodyLIG3 适用: 人, 小鼠, 大鼠, 犬, 马, 兔, Bat, Hamster, 猴 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T
Validation: KO/KD, Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.15 mg/mL
- 缓冲液
- 1XPBS pH 7, 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair." in: Nucleic acids research, Vol. 43, Issue 2, pp. 875-92, (2015) (PubMed).
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: "DNA ligase III acts as a DNA strand break sensor in the cellular orchestration of DNA strand break repair." in: Nucleic acids research, Vol. 43, Issue 2, pp. 875-92, (2015) (PubMed).
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- 抗原
- LIG3 (Ligase III, DNA, ATP-Dependent (LIG3))
- 别名
- DNA ligase 3 (LIG3 产品)
- 别名
- orf36 antibody, DDBDRAFT_0218523 antibody, DDBDRAFT_0232266 antibody, DDB_0218523 antibody, DDB_0232266 antibody, LIG3 antibody, wu:fb12c02 antibody, wu:fd10b03 antibody, wu:fm79b09 antibody, LIG2 antibody, D11Wsu78e antibody, An02g06890 antibody, AO090003000668 antibody, lig3 antibody, DNA ligase III antibody, BRCT domain-containing protein antibody, DNA ligase 3 antibody, ligase III, DNA, ATP-dependent antibody, ligase III, DNA, ATP-dependent L homeolog antibody, orf36 antibody, lig3 antibody, LIG3 antibody, Lig3 antibody, Bm1_22840 antibody, ANI_1_2644024 antibody, AOR_1_1174154 antibody, LOC100634887 antibody, lig3.L antibody
- 背景
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This gene is a member of the DNA ligase family. Each member of this family encodes a protein that catalyzes the joining of DNA ends but they each have a distinct role in DNA metabolism. The protein encoded by this gene is involved in excision repair and is located in both the mitochondria and nucleus, with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus. Additionally, alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Cellular Localization: Nucleus - 分子量
- 113 kDa
- 基因ID
- 3980
- UniProt
- P49916
- 途径
- DNA Damage Repair
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