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SP1 抗体 (C-Term)

SP1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855540
发货至: 中国
  • 抗原 See all SP1 抗体
    SP1 (Sp1 Transcription Factor (SP1))
    抗原表位
    • 21
    • 12
    • 10
    • 7
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 88
    • 60
    • 39
    • 11
    • 8
    • 7
    • 6
    • 5
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 1
    宿主
    • 90
    • 13
    • 3
    克隆类型
    • 83
    • 23
    多克隆
    标记
    • 72
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    This SP1 antibody is un-conjugated
    应用范围
    • 91
    • 46
    • 45
    • 37
    • 21
    • 16
    • 14
    • 13
    • 12
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    产品特性
    Rabbit Polyclonal antibody to SP1 (Sp1 transcription factor)
    SP1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human SP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product SP1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: THP-1

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    SP1 (Sp1 Transcription Factor (SP1))
    别名
    Sp1 transcription factor (SP1 产品)
    背景
    Transcription factor that can activate or repress transcription in response to physiological and pathological stimuli. Binds with high affinity to GC-rich motifs and regulates the expression of a large number of genes involved in a variety of processes such as cell growth, apoptosis, differentiation and immune responses. Highly regulated by post-translational modifications (phosphorylations, sumoylation, proteolytic cleavage, glycosylation and acetylation). Binds also the PDGFR-alpha G-box promoter. May have a role in modulating the cellular response to DNA damage. Implicated in chromatin remodeling. Plays a role in the recruitment of SMARCA4/BRG1 on the c-FOS promoter. Plays an essential role in the regulation of FE65 gene expression.

    Cellular Localization: Nucleus
    分子量
    81 kDa
    基因ID
    6667
    UniProt
    P08047
    途径
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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