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IL-10RA 抗体

IL10RA 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855471
发货至: 中国
  • 抗原 See all IL-10RA (IL10RA) 抗体
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This IL-10RA antibody is un-conjugated
    应用范围
    • 67
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to IL10 Receptor alpha (interleukin 10 receptor, alpha)
    IL10 Receptor alpha antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human IL10 Receptor alpha. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product IL10RA Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Validation:Orthogonal, Overexpression

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.85 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    IL-10RA (IL10RA) (Interleukin 10 Receptor, alpha (IL10RA))
    别名
    interleukin 10 receptor subunit alpha (IL10RA 产品)
    别名
    IL10R1 antibody, IL10RA antibody, CD210 antibody, CD210a antibody, CDW210A antibody, HIL-10R antibody, IL-10R1 antibody, IL10R antibody, AW553859 antibody, CDw210 antibody, CDw210a antibody, Il10r antibody, mIL-10R antibody, interleukin 10 receptor subunit alpha antibody, interleukin 10 receptor, alpha antibody, IL10RA antibody, Il10ra antibody
    背景
    The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    63 kDa
    基因ID
    3587
    UniProt
    Q13651
    途径
    Growth Factor Binding
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