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NFE2 抗体 (Center)

NFE2 适用: 人, 小鼠 WB, IF, IP, ICC, ChIP-seq 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855460
发货至: 中国
  • 抗原 See all NFE2 抗体
    NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
    抗原表位
    • 15
    • 8
    • 8
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Center
    适用
    • 46
    • 14
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    人, 小鼠
    宿主
    • 44
    • 2
    克隆类型
    • 44
    • 2
    多克隆
    标记
    • 15
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This NFE2 antibody is un-conjugated
    应用范围
    • 39
    • 19
    • 13
    • 13
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC), ChIP DNA-Sequencing (ChIP-seq)
    交叉反应
    猴, 猪
    交叉反应 (详细)
    Monkey (97 %), Pig (91 %)
    产品特性
    Rabbit Polyclonal antibody to NF-E2 (nuclear factor (erythroid-derived 2), 45 kDa)
    NF-E2 antibody [N1C3]
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human NF-E2. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product NFE2 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* Immunoprecipitation Assay-dependent dilution Western blot 1:500-1:3000* ChIP-sequencing Assay-dependent dilution Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* ImmunoprecipitationAssay-dependent dilution Western blot1:500-1:3000* ChIP-sequencingAssay-dependent dilution
    说明

    Positive Control: 293T , mouse spleen

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.03 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    NFE2 (Nuclear Factor (Erythroid-Derived 2), 45kDa (NFE2))
    别名
    NF-E2 (NFE2 产品)
    别名
    NF-E2 antibody, p45 antibody, 45kDa antibody, p45NFE2 antibody, p45nf-e2 antibody, nuclear factor, erythroid 2 antibody, nuclear factor, erythroid derived 2 antibody, NFE2 antibody, Nfe2 antibody
    背景
    Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

    Cellular Localization: Nucleus
    分子量
    41 kDa
    基因ID
    4778
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