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MUSK 抗体 (N-Term)

MUSK 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855416
发货至: 中国
  • 抗原 See all MUSK 抗体
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    抗原表位
    • 15
    • 10
    • 8
    • 8
    • 7
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 72
    • 29
    • 25
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    宿主
    • 66
    • 8
    • 2
    克隆类型
    • 71
    • 8
    多克隆
    标记
    • 39
    • 5
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    • 4
    • 4
    • 3
    • 1
    • 1
    • 1
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    • 1
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    • 1
    • 1
    • 1
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    This MUSK antibody is un-conjugated
    应用范围
    • 66
    • 35
    • 30
    • 14
    • 13
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 1
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鼠, 大鼠, 牛
    交叉反应 (详细)
    Mouse (97 %), Rat (98 %), Bovine (97 %)
    产品特性
    Rabbit Polyclonal antibody to MUSK (muscle, skeletal, receptor tyrosine kinase)
    MUSK antibody [N1N2], N-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human MUSK. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MUSK Primary Antibody
  • 应用备注
    Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: NT2D1

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MUSK (Muscle, Skeletal, Receptor Tyrosine Kinase (MUSK))
    别名
    MUSK (MUSK 产品)
    别名
    unp antibody, fj98e12 antibody, zgc:63467 antibody, wu:fj98e12 antibody, si:dz46m7.2 antibody, si:dz57f23.3 antibody, si:busm1-57f23.3 antibody, musk-A antibody, MuSK antibody, MUSK antibody, Mdk4 antibody, Mlk antibody, Nsk1 antibody, Nsk2 antibody, Nsk3 antibody, muscle antibody, muscle associated receptor tyrosine kinase antibody, muscle, skeletal, receptor tyrosine kinase antibody, muscle associated receptor tyrosine kinase S homeolog antibody, MUSK antibody, musk antibody, musk.S antibody, Musk antibody
    背景
    Intercellular communication is often mediated by receptors on the surface of one cell that recognize and are activated by specific protein ligands released by other cells. Members of one class of cell surface receptors, receptor tyrosine kinases (RTKs), are characterized by having a cytoplasmic domain containing intrinsic tyrosine kinase activity. This kinase activity is regulated by the binding of a cognate ligand to the extracellular portion of the receptor. DeChiara et al. (1996) [PubMed 8653786] noted that the RTKs, known to be expressed in cell type-specific fashions, play a role critical for the growth and differentiation of those cell types. For example, members of the neural-specific TRK family that recognize nerve growth factor are absolutely required for the survival and development of discrete neuronal subpopulations, and the receptor tyrosine kinases TIE1 (MIM 600222) and TIE2 (MIM 600221) play a critical role in the development of normal blood vessels.[supplied by OMIM]

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    97 kDa
    基因ID
    4593
    途径
    RTK signaling, Regulation of Muscle Cell Differentiation, Synaptic Membrane, Regulation of Cell Size, Skeletal Muscle Fiber Development
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