GABBR1 抗体
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- 抗原 See all GABBR1 抗体
- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GABBR1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to GABA B Receptor 1 (gamma-aminobutyric acid (GABA) B receptor, 1)
GABA B Receptor 1 antibody [N2C1], Internal - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human GABA B Receptor 1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product GABBR1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: PC-3 , U87-MG , SK-N-SH , C8D30
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.43 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- GABBR1 (gamma-aminobutyric Acid (GABA) B Receptor, 1 (GABBR1))
- 别名
- gamma-aminobutyric acid type B receptor subunit 1 (GABBR1 产品)
- 别名
- GABABR1 antibody, GABBR1-3 antibody, GB1 antibody, GPRC3A antibody, dJ271M21.1.1 antibody, dJ271M21.1.2 antibody, gabbr1 antibody, GABBR1 antibody, GABA(B)R1 antibody, GABAB1 antibody, GABAbR1 antibody, bM573K1.1 antibody, gamma-aminobutyric acid type B receptor subunit 1 antibody, gamma-aminobutyric acid (GABA) B receptor, 1a antibody, gamma-aminobutyric acid (GABA) B receptor, 1 antibody, GABBR1 antibody, gabbr1a antibody, gabbr1 antibody, Gabbr1 antibody
- 背景
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Gamma-aminobutyric acid (GABA) is the main inhibitory neurotransmitter in the mammalian central nervous system. GABA exerts its effects through ionotropic [GABA(A/C)] receptors, to produce fast synaptic inhibition, and metabotropic [GABA(B)] receptors, to produce slow, prolonged inhibitory signals. The GABA(B) receptor consists of a heterodimer of two related 7-transmembrane receptors, GABA(B) receptor 1 and GABA(B) receptor 2. The GABA(B) receptor 1 gene is mapped to chromosome 6p21.3 within the HLA class I region close to the HLA-F gene. Susceptibility loci for multiple sclerosis, epilepsy, and schizophrenia have also been mapped in this region. Alternative splicing of this gene generates 4 transcript variants.
Cellular Localization: Cell membrane, Multi-pass membrane protein , Cell junction , synapse , postsynaptic cell membrane, Multi-pass membrane protein , Isoform 1E: Secreted - 分子量
- 108 kDa
- 基因ID
- 2550
- UniProt
- Q9UBS5
- 途径
- Positive Regulation of Peptide Hormone Secretion, cAMP Metabolic Process
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