PYCARD 抗体
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- 抗原 See all PYCARD 抗体
- PYCARD (PYD and CARD Domain Containing (PYCARD))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PYCARD antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to TMS1 (PYD and CARD domain containing)
TMS1 antibody [N1C3] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human TMS1. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PYCARD Primary Antibody
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anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibody
PYCARD 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 50-195) antibodyPYCARD 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (C-Term) antibodyVerified PYCARD 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人 WB, IHC, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-120) antibodyPYCARD 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 1C3D3 unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (Internal Region) antibodyVerified PYCARD 适用: 人, 小鼠, 大鼠 ELISA, IF 宿主: 山羊 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-149) antibodyPYCARD 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (N-Term) antibodyPYCARD 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) (AA 1-195) antibodyPYCARD 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-PYD and CARD Domain Containing (PYCARD) antibodyPYCARD 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: THP-1 , DDDDK-tagged PYCARD-transfected 293T
Validation: Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- PYCARD (PYD and CARD Domain Containing (PYCARD))
- 别名
- PYD and CARD domain containing (PYCARD 产品)
- 别名
- ASC antibody, CARD5 antibody, TMS antibody, TMS-1 antibody, TMS1 antibody, 9130417A21Rik antibody, Asc antibody, TNS1 antibody, masc antibody, asc1 antibody, zAsc antibody, zgc:109874 antibody, PYD and CARD domain containing antibody, PYCARD antibody, Pycard antibody, pycard antibody
- 背景
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This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm, however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Cytoplasm - 分子量
- 22 kDa
- 基因ID
- 29108
- UniProt
- Q9ULZ3
- 途径
- Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Actin Filament Polymerization, Positive Regulation of Endopeptidase Activity, Activated T Cell Proliferation, Inflammasome
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