BAG2 抗体
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- 抗原 See all BAG2 抗体
- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This BAG2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to BAG2 (BAG family molecular chaperone regulator 2)
BAG2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human BAG2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product BAG2 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: A431 , HeLa
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- BAG2 (BCL2-Associated Athanogene 2 (BAG2))
- 别名
- BCL2 associated athanogene 2 (BAG2 产品)
- 别名
- bag2 antibody, MGC89300 antibody, BAG2 antibody, ATBAG2 antibody, BCL-2-associated athanogene 2 antibody, MTG10.13 antibody, MTG10_13 antibody, BAG-2 antibody, dJ417I1.2 antibody, zgc:64195 antibody, 2610042A13Rik antibody, BC016230 antibody, BCL2 associated athanogene 2 antibody, BCL-2-associated athanogene 2 antibody, BCL2-associated athanogene 2 antibody, Bcl2-associated athanogene 2 antibody, bag2 antibody, BAG2 antibody, Bag2 antibody
- 背景
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BAG proteins compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The predicted BAG2 protein contains 211 amino acids. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.
- 分子量
- 24 kDa
- 基因ID
- 9532
- UniProt
- O95816
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