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AIF 抗体 (N-Term)

AIFM1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855383
发货至: 中国
  • 抗原 See all AIF (AIFM1) 抗体
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    抗原表位
    • 15
    • 9
    • 8
    • 8
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 104
    • 58
    • 55
    • 22
    • 11
    • 11
    • 7
    • 7
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    宿主
    • 92
    • 9
    • 2
    • 2
    克隆类型
    • 89
    • 15
    多克隆
    标记
    • 63
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This AIF antibody is un-conjugated
    应用范围
    • 80
    • 35
    • 31
    • 27
    • 21
    • 14
    • 13
    • 12
    • 12
    • 7
    • 5
    • 4
    • 2
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    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    产品特性
    Rabbit Polyclonal antibody to AIF (apoptosis-inducing factor, mitochondrion-associated, 1)
    AIF antibody [N1N2], N-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human AIF. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product AIFM1 Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: 293T , A431 , HeLa , HepG2 , A375

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.72 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    AIF (AIFM1) (Apoptosis-Inducing Factor, Mitochondrion-Associated, 1 (AIFM1))
    别名
    AIF (AIFM1 产品)
    背景
    This gene encodes a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. Induction of apoptosis results in the translocation of this protein to the nucleus where it effects chromosome condensation and fragmentation. In addition, this gene product induces mitochondria to release the apoptogenic proteins cytochrome c and caspase-9. Several alternative transcripts encoding different isoforms have been identified for this gene.

    Cellular Localization: Mitochondrion intermembrane space , Nucleus
    分子量
    67 kDa
    基因ID
    9131
    途径
    Apoptosis, Positive Regulation of Endopeptidase Activity, Cell RedoxHomeostasis, Smooth Muscle Cell Migration, Warburg Effect
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