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- 抗原 See all NLRC4 抗体
- NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
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抗原表位
- N-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NLRC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to CARD12 (NLR family, CARD domain containing 4)
CARD12 antibody [N1], N-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human CARD12. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product NLRC4 Primary Antibody
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anti-NLR Family, CARD Domain Containing 4 (NLRC4) antibody
NLRC4 适用: 人, 小鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (AA 1-250) antibodyNLRC4 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (pSer533) antibodyNLRC4 适用: 人, 小鼠 WB, ELISA, ICC 宿主: 大鼠 Monoclonal 4B7B7 unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) antibodyNLRC4 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (C-Term) antibodyNLRC4 适用: 人 WB, IHC, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (AA 941-990) antibodyNLRC4 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (C-Term) antibodyNLRC4 适用: 人, 小鼠, 大鼠, 豚鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (AA 1-250) antibodyNLRC4 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) (AA 531-630) antibodyNLRC4 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-NLR Family, CARD Domain Containing 4 (NLRC4) antibodyNLRC4 适用: 人 WB, IF, EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MCF-7 , human NLRC4-transfected 293T cells
Validation: Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))
- 别名
- NLR family CARD domain containing 4 (NLRC4 产品)
- 别名
- CARD12 antibody, CLAN antibody, CLAN1 antibody, CLANA antibody, CLANB antibody, CLANC antibody, CLAND antibody, CLR2.1 antibody, IPAF antibody, 9530011P19Rik antibody, Card12 antibody, NLR family CARD domain containing 4 antibody, NLR family, CARD domain containing 4 antibody, NLRC4 antibody, Nlrc4 antibody
- 背景
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In C. elegans, Ced4 binds and activates Ced3, an apoptotic initiator caspase, via caspase-associated recruitment domains (CARDs). Human Ced4 homologs include APAF1 (MIM 602233), NOD1/CARD4 (MIM 605980), and NOD2/CARD15 (MIM 605956). These proteins have at least 1 N-terminal CARD domain followed by a centrally located nucleotide-binding domain (NBD or NACHT) and a C-terminal regulatory domain, found only in mammals, that contains either WD40 repeats or leucine-rich repeats (LRRs). CARD12 is a member of the Ced4 family and can induce apoptosis.[supplied by OMIM]
Cellular Localization: Cytoplasm - 分子量
- 116 kDa
- 基因ID
- 58484
- UniProt
- Q9NPP4
- 途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome
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