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ARHGEF18 抗体 (Center)

ARHGEF18 适用: 人 WB, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855329
发货至: 中国
  • 抗原 See all ARHGEF18 抗体
    ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
    抗原表位
    • 15
    • 8
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    Center
    适用
    • 49
    • 3
    • 2
    宿主
    • 46
    • 2
    • 1
    克隆类型
    • 47
    • 2
    多克隆
    标记
    • 14
    • 6
    • 5
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ARHGEF18 antibody is un-conjugated
    应用范围
    • 24
    • 24
    • 13
    • 13
    • 8
    • 7
    • 3
    • 3
    • 3
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)
    产品特性
    Rabbit Polyclonal antibody to ARHGEF18 (Rho/Rac guanine nucleotide exchange factor (GEF) 18)
    ARHGEF18 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human ARHGEF18. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* Western blot1:500-1:3000*
    说明

    Positive Control: HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.43 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Haas, Zihni, Ruppel, Hartmann, Ebnet, Tada, Balda, Matter: "Interplay between Extracellular Matrix Stiffness and JAM-A Regulates Mechanical Load on ZO-1 and Tight Junction Assembly." in: Cell reports, Vol. 32, Issue 3, pp. 107924, (2020) (PubMed).

    Lu, Wawro, Morgens, Portela, Bassik, Pfeffer: "Genome-wide interrogation of extracellular vesicle biology using barcoded miRNAs." in: eLife, Vol. 7, (2018) (PubMed).

    Zihni, Vlassaks, Terry, Carlton, Leung, Olson, Pichaud, Balda, Matter: "An apical MRCK-driven morphogenetic pathway controls epithelial polarity." in: Nature cell biology, Vol. 19, Issue 9, pp. 1049-1060, (2017) (PubMed).

  • 抗原
    ARHGEF18 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 18 (ARHGEF18))
    别名
    ARHGEF18 (ARHGEF18 产品)
    背景
    Rho GTPases are GTP binding proteins that regulate a wide spectrum of cellular functions. These cellular processes include cytoskeletal rearrangements, gene transcription, cell growth and motility. Activation of Rho GTPases is under the direct control of guanine nucleotide exchange factors (GEFs). The protein encoded by this gene is a guanine nucleotide exchange factor and belongs to the Rho GTPase GFE family. Family members share a common feature, a Dbl (DH) homology domain followed by a pleckstrin (PH) homology domain. Alternatively spliced transcript variants encoding different isoforms have been identified.

    Cellular Localization: Cytoplasm
    分子量
    131 kDa
    基因ID
    23370
    途径
    Neurotrophin Signaling Pathway
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