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Cofilin 抗体

KO Validated CFL1 适用: 人 WB, IF, IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855302
发货至: 中国
  • 抗原 See all Cofilin (CFL1) 抗体
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    适用
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    宿主
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    克隆类型
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    多克隆
    标记
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    This Cofilin antibody is un-conjugated
    应用范围
    • 74
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to Cofilin 1 (cofilin 1 (non-muscle))
    Cofilin 1 antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Cofilin 1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product CFL1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    Validation: KO/KD, Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Lee, Du, Hwa, Kim: "Parkin Coordinates Platelet Stress Response in Diabetes Mellitus: A Big Role in a Small Cell." in: International journal of molecular sciences, Vol. 21, Issue 16, (2020) (PubMed).

    Chen, Lin, Tsai, He, Luo, Chiu, Herschman, Li: "Exosomal 2',3'-CNP from mesenchymal stem cells promotes hippocampus CA1 neurogenesis/neuritogenesis and contributes to rescue of cognition/learning deficiencies of damaged brain." in: Stem cells translational medicine, Vol. 9, Issue 4, pp. 499-517, (2020) (PubMed).

  • 抗原
    Cofilin (CFL1) (Cofilin 1 (CFL1))
    别名
    cofilin 1 (CFL1 产品)
    别名
    cfl1 antibody, xac1 antibody, xac2 antibody, cfl antibody, cb86 antibody, sb:cb86 antibody, zgc:56501 antibody, wu:fb18a04 antibody, wu:fk77b03 antibody, 12/8 antibody, ADF antibody, ADF/cofilin antibody, Adf antibody, CG4254 antibody, Cadf antibody, D-cof antibody, D61 antibody, Dmel\\CG4254 antibody, T8 antibody, Tsr antibody, cofilin antibody, cofilin/ADF antibody, cofilin/actin depolymerizing factor homolog antibody, l(2)03101 antibody, l(2)k03101 antibody, l(2)k05633 antibody, l(2)k13409 antibody, ntf antibody, CFL antibody, AA959946 antibody, Cof antibody, CFL1 antibody, cofilin 1 (non-muscle) L homeolog antibody, cofilin 1 (non-muscle) antibody, cofilin 1 (non-muscle), like antibody, cofilin 1 antibody, twinstar antibody, cofilin antibody, cofilin 1, non-muscle antibody, Contrafreeloading antibody, cfl1.L antibody, cfl1 antibody, cfl1l antibody, CFL1 antibody, tsr antibody, COF1 antibody, TSTA_042790 antibody, Cfl1 antibody, CFL antibody
    背景
    Cofilin is a widely distributed intracellular actin-modulating protein that binds and depolymerizes filamentous F-actin and inhibits the polymerization of monomeric G-actin in a pH -dependent manner. It is involved in the translocation of actin-cofilin complex from cytoplasm to nucleus.[supplied by OMIM]

    Cellular Localization: Nucleus matrix , Cytoplasm , cytoskeleton
    分子量
    19 kDa
    基因ID
    1072
    UniProt
    P23528
    途径
    Regulation of Cell Size, Tube Formation, Protein targeting to Nucleus, CXCR4-mediated Signaling Events
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