Prohibitin 2 抗体
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- 抗原 See all Prohibitin 2 (PHB2) 抗体
- Prohibitin 2 (PHB2)
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Prohibitin 2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit Polyclonal antibody to Prohibitin 2 (prohibitin 2)
Prohibitin 2 antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Prohibitin 2. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product PHB2 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Mouse brain , H1299 , HeLa
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.66 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- Prohibitin 2 (PHB2)
- 别名
- prohibitin 2 (PHB2 产品)
- 背景
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Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Cellular Localization: Mitochondrion inner membrane (By similarity) , Cytoplasm (By similarity) , Nucleus (By similarity) - 分子量
- 33 kDa
- 基因ID
- 11331
- UniProt
- Q99623
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
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