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ACTC1 抗体

ACTC1 适用: 人 WB, IHC (p), ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855212
发货至: 中国
  • 抗原 See all ACTC1 抗体
    ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))
    适用
    • 36
    • 26
    • 24
    • 9
    • 5
    • 4
    • 3
    • 3
    • 2
    宿主
    • 21
    • 17
    克隆类型
    • 19
    • 19
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This ACTC1 antibody is un-conjugated
    应用范围
    • 23
    • 12
    • 9
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC), Immunofluorescence (IF)
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to alpha Cardiac Muscle Actin (actin, alpha, cardiac muscle 1)
    alpha Cardiac Muscle Actin antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human alpha Cardiac Muscle Actin. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: PC-12 , Rat2 , Jurkat , Raji , K562 , THP-1 , NIH-3T3 , JC , BCL-1 , Rat muscle

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.56 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Henry, Szabó, Sutus, Pirity: "RYBP is important for cardiac progenitor cell development and sarcomere formation." in: PLoS ONE, Vol. 15, Issue 7, pp. e0235922, (2020) (PubMed).

    Oldershaw, Owens, Sutherland, Linney, Liddle, Magana, Lash, Gill, Richardson, Meeson: "Human Cardiac-Mesenchymal Stem Cell-Like Cells, a Novel Cell Population with Therapeutic Potential." in: Stem cells and development, Vol. 28, Issue 9, pp. 593-607, (2020) (PubMed).

    Miksiunas, Rucinskas, Janusauskas, Labeit, Bironaite: "Histone Deacetylase Inhibitor Suberoylanilide Hydroxamic Acid Improves Energetic Status and Cardiomyogenic Differentiation of Human Dilated Myocardium-Derived Primary Mesenchymal Cells." in: International journal of molecular sciences, Vol. 21, Issue 14, (2020) (PubMed).

    Robertson, Wen, Yin, Chen, Smith, Paine: "Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells." in: Frontiers in physiology, Vol. 8, pp. 336, (2017) (PubMed).

  • 抗原
    ACTC1 (Actin, Alpha, Cardiac Muscle 1 (ACTC1))
    别名
    actin alpha cardiac muscle 1 (ACTC1 产品)
    别名
    acta1 antibody, actc antibody, fa27h01 antibody, fb83f06 antibody, wu:fa27h01 antibody, wu:fb83f06 antibody, ACTC antibody, ASD5 antibody, CMD1R antibody, CMH11 antibody, LVNC4 antibody, Actc-1 antibody, actcl antibody, actc1l antibody, cmd1r antibody, ACTC1 antibody, actin, alpha, cardiac muscle 1 L homeolog antibody, actin, alpha, cardiac muscle 1b antibody, actin, alpha, cardiac muscle 1 antibody, actin, alpha, cardiac muscle 1a antibody, actc1.L antibody, actc1b antibody, ACTC1 antibody, Actc1 antibody, actc1a antibody, actc1 antibody
    背景
    Actins are highly conserved proteins that are involved in various types of cell motility. Polymerization of globular actin (G-actin) leads to a structural filament (F-actin) in the form of a two-stranded helix. Each actin can bind to four others. The protein encoded by this gene belongs to the actin family which is comprised of three main groups of actin isoforms, alpha, beta, and gamma. The alpha actins are found in muscle tissues and are a major constituent of the contractile apparatus. Defects in this gene have been associated with idiopathic dilated cardiomyopathy (IDC) and familial hypertrophic cardiomyopathy (FHC).

    Cellular Localization: Cytoplasm , cytoskeleton
    分子量
    42 kDa
    基因ID
    70
    UniProt
    P68032
    途径
    Myometrial Relaxation and Contraction
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