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EIF4G2 抗体 (C-Term)

EIF4G2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855138
发货至: 中国
  • 抗原 See all EIF4G2 抗体
    EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
    抗原表位
    • 15
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    C-Term
    适用
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    宿主
    • 57
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    克隆类型
    • 58
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    多克隆
    标记
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    This EIF4G2 antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to DAP5 (eukaryotic translation initiation factor 4 gamma, 2)
    DAP5 antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human DAP5. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product EIF4G2 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse brain , HeLa , HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.39 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))
    别名
    eukaryotic translation initiation factor 4 gamma 2 (EIF4G2 产品)
    背景
    Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3, eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described.

    分子量
    102 kDa
    基因ID
    1982
    UniProt
    P78344
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