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Calnexin 抗体 (Internal Region)

CANX 适用: 人, 小鼠, 大鼠 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855124
发货至: 中国
  • 抗原 See all Calnexin (CANX) 抗体
    Calnexin (CANX)
    抗原表位
    • 49
    • 17
    • 13
    • 6
    • 5
    • 5
    • 5
    • 2
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    • 2
    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    Internal Region
    适用
    • 121
    • 78
    • 77
    • 48
    • 34
    • 31
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    • 25
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    • 1
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    • 1
    • 1
    人, 小鼠, 大鼠
    宿主
    • 120
    • 24
    • 7
    克隆类型
    • 120
    • 32
    多克隆
    标记
    • 69
    • 8
    • 7
    • 5
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
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    • 1
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    • 1
    • 1
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    This Calnexin antibody is un-conjugated
    应用范围
    • 121
    • 78
    • 58
    • 55
    • 39
    • 29
    • 26
    • 26
    • 21
    • 14
    • 13
    • 9
    • 8
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    小鸡, 犬, 非洲爪蟾, 斑马鱼, 牛
    交叉反应 (详细)
    Chicken (91 %), Dog (94 %), Xenopus laevis (88 %), Zebrafish (82 %), Bovine (94 %)
    产品特性
    Rabbit Polyclonal antibody to Calnexin (calnexin)
    Calnexin antibody [N3C2], Internal
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Calnexin. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product CANX Primary Antibody
  • 应用备注
    Suggested dilution Reference ICC/IF 1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:10000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceICC/IF1:100-1:1000* IHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:10000*
    说明

    Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji , NIH-3T3 , PC-12 , Rat2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.87 mg/mL
    缓冲液
    0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • de Jong, Murphy, Mäger, Willms, Garcia-Guerra, Gitz-Francois, Lefferts, Gupta, Steenbeek, van Rheenen, El Andaloussi, Schiffelers, Wood, Vader: "A CRISPR-Cas9-based reporter system for single-cell detection of extracellular vesicle-mediated functional transfer of RNA." in: Nature communications, Vol. 11, Issue 1, pp. 1113, (2020) (PubMed).

    Ilahibaks, Lei, Mol, Deshantri, Jiang, Schiffelers, Vader, Sluijter: "Biofabrication of Cell-Derived Nanovesicles: A Potential Alternative to Extracellular Vesicles for Regenerative Medicine." in: Cells, Vol. 8, Issue 12, (2020) (PubMed).

    Sever, Vo, Bols, Dixon: "Rainbow trout (Oncorhynchus mykiss) contain two calnexin genes which encode distinct proteins." in: Developmental and comparative immunology, Vol. 42, Issue 2, pp. 211-9, (2014) (PubMed).

  • 抗原
    Calnexin (CANX)
    别名
    Calnexin (CANX 产品)
    别名
    CNX antibody, IP90 antibody, P90 antibody, 1110069N15Rik antibody, AI988026 antibody, Cnx antibody, D11Ertd153e antibody, canx antibody, clgn antibody, clnx antibody, cnx antibody, PP90 antibody, zgc:63524 antibody, wu:fe06b12 antibody, CANX antibody, calnexin antibody, CalNeXin antibody, calnexin L homeolog antibody, CANX antibody, Canx antibody, cnx-1 antibody, canx.L antibody, canx antibody, LOC100283947 antibody
    背景
    This gene encodes a member of the calnexin family of molecular chaperones. The encoded protein is a calcium-binding, endoplasmic reticulum (ER)-associated protein that interacts transiently with newly synthesized N-linked glycoproteins, facilitating protein folding and assembly. It may also play a central role in the quality control of protein folding by retaining incorrectly folded protein subunits within the ER for degradation. Alternatively spliced transcript variants encoding the same protein have been described.

    Cellular Localization: Endoplasmic reticulum membrane , Melanosome
    分子量
    68 kDa
    基因ID
    821
    途径
    MAPK Pathway, Thyroid Hormone Synthesis
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