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alpha Actinin 4 抗体 (C-Term)

Name: alpha Actinin 4 抗体 (C-Term)
Brand: antibodies-online
SKU: ABIN2855119
Availability: OutOfStock

ACTN4 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

WB Image alpha Actinin 4 antibody [C2C3], C-term detects ACTN4 protein by Western blot analysis. (alpha Actinin 4 抗体 (C-Term))

IHC-P Image alpha Actinin 4 antibody [C2C3], C-term detects alpha Actinin 4 protein on mouse intestine by immunohistochemical analysis. (alpha Actinin 4 抗体 (C-Term))

IHC

WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 5% SDS PAGE antibody diluted at 1:1000 (alpha Actinin 4 抗体 (C-Term))

IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using alpha Actinin 4, antibody at 1:500 dilution. (alpha Actinin 4 抗体 (C-Term))

IHC

ICC/IF Image Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using alpha Actinin 4, antibody (Green) at 1:500 dilution. (alpha Actinin 4 抗体 (C-Term))

7 images

产品编号 ABIN2855119

发货至: 中国

Datasheet as PDF

抗原 See all alpha Actinin 4 (ACTN4) 抗体

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))
抗原表位
10

6

6

4

4

3

2

2

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1

1
C-Term
适用
91

50

46

8

5

4

4

3

3

3

2

2

1

1

1
人
宿主
84

7
兔
Compatible Secondaries
克隆类型
72

18
多克隆
标记
55

6

6

3

2

2

2

2

2

2

1

1

1

1

1

1

1

1

1
This alpha Actinin 4 antibody is un-conjugated
应用范围
68

31

26

17

16

14

13

12

7

2

2

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

交叉反应

人, 小鼠, 大鼠

产品特性

Rabbit Polyclonal antibody to alpha Actinin 4 (actinin, alpha 4)
alpha Actinin 4 antibody [C2C3], C-term

纯化方法

Purified by antigen-affinity chromatography.

免疫原

Recombinant protein encompassing a sequence within the C-terminus region of human alpha Actinin 4. The exact sequence is proprietary.

亚型

IgG

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anti-Actinin, alpha 4 (ACTN4) (N-Term) antibody
ACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼, 马, 兔 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) antibody
ACTN4 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 1-911) antibody
ACTN4 适用: 人 WB, IF, PLA 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 561-661) antibody
ACTN4 适用: 人, 小鼠, 大鼠 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Actinin, alpha 4 (ACTN4) (AA 785-813), (C-Term) antibody
ACTN4 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB15705 unconjugated

anti-Actinin, alpha 4 (ACTN4) (C-Term) antibody
ACTN4 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated

应用备注

WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

说明

Positive Control: 293T , A431 , HeLa , HepG2 , A375 , Neuro2A , GL261 , C8D30 , NIH-3T3 , BCL-1 , Raw264.7 , C2C12 , Mouse brain , PC-12

限制

仅限研究用
状态

Liquid

浓度

0.32 mg/mL

缓冲液

0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal

储存液

Thimerosal (Merthiolate)

注意事项

This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

储存条件

4 °C,-20 °C

储存方法

Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
抗原

alpha Actinin 4 (ACTN4) (Actinin, alpha 4 (ACTN4))

别名

actinin alpha 4 (ACTN4 产品)

别名

fsgs antibody, fsgs1 antibody, C77391 antibody, ACTININ-4 antibody, FSGS antibody, FSGS1 antibody, wu:fb53f05 antibody, zgc:63508 antibody, actinin alpha 4 antibody, actinin, alpha 4 antibody, actinin alpha 4 S homeolog antibody, actn4 antibody, ACTN4 antibody, Actn4 antibody, actn4.S antibody

背景

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis.

Cellular Localization: Nucleus , Cytoplasm

分子量

105 kDa

基因ID

81

UniProt

O43707

途径

Proton Transport