(1 reference)-
- 抗原 See all DOK1 抗体
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This DOK1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 产品特性
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Rabbit Polyclonal antibody to DOK1 (docking protein 1, 62 kDa (downstream of tyrosine kinase 1))
DOK1 antibody [N1C1] - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human p62Dok. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product DOK1 Primary Antibody
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anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-280) antibody
DOK1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) antibodyDOK1 适用: 人, 小鼠, 大鼠 IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (Internal Region) antibodyDOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) antibodyDOK1 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr362) antibodyDOK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) antibodyDOK1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr398) antibodyDOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr362) antibodyDOK1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (pTyr398) antibodyDOK1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1) (AA 1-481) antibodyDOK1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Raji
Validation: Orthogonal
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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: "Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).
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: "Key Players of Cisplatin Resistance: Towards a Systems Pharmacology Approach." in: International journal of molecular sciences, Vol. 19, Issue 3, (2018) (PubMed).
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- 抗原
- DOK1 (Docking Protein 1, 62kDa (Downstream of tyrosine Kinase 1) (DOK1))
- 别名
- docking protein 1 (DOK1 产品)
- 别名
- P62DOK antibody, Dok-1 antibody, AW557123 antibody, p62DOK antibody, dok1 antibody, zgc:76914 antibody, docking protein 1 antibody, docking protein 1b antibody, DOK1 antibody, Dok1 antibody, dok1b antibody
- 背景
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Docking protein 1 is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. Docking protein 1 contains a putative pleckstrin homology domain at the amino terminus and ten PXXP SH3 recognition motifs. Docking protein 2 binds p120 (RasGAP) from CML cells. It has been postulated to play a role in mitogenic signaling.
- 分子量
- 52 kDa
- 基因ID
- 1796
- UniProt
- Q99704
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