alpha Adducin 抗体
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- 抗原 See all alpha Adducin (ADD1) 抗体
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This alpha Adducin antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 产品特性
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Rabbit Polyclonal antibody to alpha Adducin (adducin 1 (alpha))
alpha Adducin antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human alpha Adducin. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ADD1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: Jurkat , Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.81 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
- 别名
- adducin 1 (ADD1 产品)
- 别名
- ADDA antibody, AI256389 antibody, alpha-adducin antibody, bZ1H20.1 antibody, cb787 antibody, zgc:158352 antibody, add2 antibody, adda antibody, add1-a antibody, ADD1 antibody, adducin 1 antibody, adducin 1 (alpha) antibody, adducin 1 S homeolog antibody, ADD1 antibody, Add1 antibody, add1 antibody, add1.S antibody
- 背景
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Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.
Cellular Localization: Cytoplasm , cytoskeleton , Cell membrane - 分子量
- 81 kDa
- 基因ID
- 118
- UniProt
- P35611
- 途径
- Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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