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alpha Adducin 抗体

ADD1 适用: 人 WB, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855094
发货至: 中国
  • 抗原 See all alpha Adducin (ADD1) 抗体
    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
    适用
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    宿主
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    克隆类型
    • 90
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    多克隆
    标记
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    This alpha Adducin antibody is un-conjugated
    应用范围
    • 60
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    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠
    产品特性
    Rabbit Polyclonal antibody to alpha Adducin (adducin 1 (alpha))
    alpha Adducin antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human alpha Adducin. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ADD1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Jurkat , Raji

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.81 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    alpha Adducin (ADD1) (Adducin 1 (Alpha) (ADD1))
    别名
    adducin 1 (ADD1 产品)
    别名
    ADDA antibody, AI256389 antibody, alpha-adducin antibody, bZ1H20.1 antibody, cb787 antibody, zgc:158352 antibody, add2 antibody, adda antibody, add1-a antibody, ADD1 antibody, adducin 1 antibody, adducin 1 (alpha) antibody, adducin 1 S homeolog antibody, ADD1 antibody, Add1 antibody, add1 antibody, add1.S antibody
    背景
    Adducins are a family of cytoskeleton proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related subunits, which are produced from distinct genes but share a similar structure. Alpha- and beta-adducin include a protease-resistant N-terminal region and a protease-sensitive, hydrophilic C-terminal region. Alpha- and gamma-adducins are ubiquitously expressed. In contrast, beta-adducin is expressed at high levels in brain and hematopoietic tissues. Adducin binds with high affinity to Ca(2+)/calmodulin and is a substrate for protein kinases A and C. Alternative splicing results in multiple variants encoding distinct isoforms, however, not all variants have been fully described.

    Cellular Localization: Cytoplasm , cytoskeleton , Cell membrane
    分子量
    81 kDa
    基因ID
    118
    UniProt
    P35611
    途径
    Negative Regulation of Hormone Secretion, Regulation of Actin Filament Polymerization, Regulation of Lipid Metabolism by PPARalpha, ER-Nucleus Signaling
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