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ALDOB 抗体

ALDOB 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855024
发货至: 中国
  • 抗原 See all ALDOB 抗体
    ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
    适用
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    宿主
    • 51
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    克隆类型
    • 53
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    多克隆
    标记
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    This ALDOB antibody is un-conjugated
    应用范围
    • 54
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF), Immunocytochemistry (ICC)
    交叉反应
    人, 小鼠, 大鼠, Turtle
    产品特性
    Rabbit Polyclonal antibody to Aldolase B (aldolase B, fructose-bisphosphate)
    Aldolase B antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human Aldolase B. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Neuro2A , GL261 , C8D30 , PC-12 , mouse brain , rat brain , 293T , A431 , HeLa , HepG2

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.09 mg/mL
    缓冲液
    1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Chen, Lin, Chen, Cheng, Cheng, Imai et al.: "Effect of prednisolone on glyoxalase 1 in an inbred mouse model of aristolochic acid nephropathy using a proteomics method with fluorogenic derivatization-liquid chromatography-tandem mass ..." in: PLoS ONE, Vol. 15, Issue 1, pp. e0227838, (2020) (PubMed).

    Dawson, Biggar, Storey: "Characterization of fructose-1,6-bisphosphate aldolase during anoxia in the tolerant turtle, Trachemys scripta elegans: an assessment of enzyme activity, expression and structure." in: PLoS ONE, Vol. 8, Issue 7, pp. e68830, (2014) (PubMed).

  • 抗原
    ALDOB (Aldolase B, Fructose-Bisphosphate (ALDOB))
    别名
    aldolase, fructose-bisphosphate B (ALDOB 产品)
    别名
    aldb antibody, aldo2 antibody, xaldb antibody, ALDOB antibody, aldob antibody, ALDB antibody, ALDO2 antibody, Aldo-2 antibody, Aldo2 antibody, BC016435 antibody, LIV10 antibody, fb25f09 antibody, wu:fb25f09 antibody, aldolase B antibody, aldolase, fructose-bisphosphate B antibody, aldolase, fructose-bisphosphate B S homeolog antibody, aldolase b, fructose-bisphosphate antibody, aldolase B, fructose-bisphosphate antibody, xaldb antibody, aldob antibody, aldob.S antibody, ALDOB antibody, Aldob antibody
    背景
    Fructose-1,6-bisphosphate aldolase (EC 4.1.2.13) is a tetrameric glycolytic enzyme that catalyzes the reversible conversion of fructose-1,6-bisphosphate to glyceraldehyde 3-phosphate and dihydroxyacetone phosphate. Vertebrates have 3 aldolase isozymes which are distinguished by their electrophoretic and catalytic properties. Differences indicate that aldolases A, B, and C are distinct proteins, the products of a family of related 'housekeeping' genes exhibiting developmentally regulated expression of the different isozymes. The developing embryo produces aldolase A, which is produced in even greater amounts in adult muscle where it can be as much as 5 % of total cellular protein. In adult liver, kidney and intestine, aldolase A expression is repressed and aldolase B is produced. In brain and other nervous tissue, aldolase A and C are expressed about equally. There is a high degree of homology between aldolase A and C. Defects in ALDOB cause hereditary fructose intolerance.

    分子量
    39 kDa
    基因ID
    229
    UniProt
    P05062
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