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ADAM17 抗体 (C-Term)

KO Validated ADAM17 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2855021
发货至: 中国
  • 抗原 See all ADAM17 抗体
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    抗原表位
    • 16
    • 8
    • 7
    • 7
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 97
    • 45
    • 43
    • 3
    • 3
    • 3
    • 1
    宿主
    • 82
    • 14
    • 1
    • 1
    • 1
    克隆类型
    • 75
    • 24
    多克隆
    标记
    • 47
    • 7
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This ADAM17 antibody is un-conjugated
    应用范围
    • 74
    • 44
    • 36
    • 15
    • 14
    • 11
    • 10
    • 10
    • 9
    • 4
    • 4
    • 4
    • 3
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to ADAM17 (ADAM metallopeptidase domain 17)
    ADAM17 antibody [C2C3], C-term
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human ADAM17. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product ADAM17 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: K562 , Raw264.7 , Rat2 , HeLa

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.21 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
    别名
    ADAM metallopeptidase domain 17 (ADAM17 产品)
    背景
    This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.

    Cellular Localization: Membrane
    分子量
    93 kDa
    基因ID
    6868
    UniProt
    P78536
    途径
    Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
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