ADAM17 抗体 (C-Term)
-
- 抗原 See all ADAM17 抗体
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
-
抗原表位
- C-Term
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This ADAM17 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
-
Rabbit Polyclonal antibody to ADAM17 (ADAM metallopeptidase domain 17)
ADAM17 antibody [C2C3], C-term - 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human ADAM17. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product ADAM17 Primary Antibody
-
-
- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
-
Positive Control: K562 , Raw264.7 , Rat2 , HeLa
Validation: KO/KD
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1.21 mg/mL
- 缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- 抗原
- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
- 别名
- ADAM metallopeptidase domain 17 (ADAM17 产品)
- 别名
- ADAM18 antibody, CD156B antibody, CSVP antibody, NISBD antibody, TACE antibody, CD156b antibody, Tace antibody, adam17 antibody, si:dkey-81b15.2 antibody, adam18 antibody, cd156b antibody, csvp antibody, tace antibody, fc20b01 antibody, wu:fc20b01 antibody, zgc:63886 antibody, ADAM metallopeptidase domain 17 antibody, a disintegrin and metallopeptidase domain 17 antibody, ADAM metallopeptidase domain 17b antibody, ADAM metallopeptidase domain 17 L homeolog antibody, ADAM metallopeptidase domain 17a antibody, ADAM17 antibody, Adam17 antibody, adam17b antibody, adam17.L antibody, adam17a antibody
- 背景
-
This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.
Cellular Localization: Membrane - 分子量
- 93 kDa
- 基因ID
- 6868
- UniProt
- P78536
- 途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
-