CASR 抗体
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- 抗原 See all CASR 抗体
- CASR (Calcium-Sensing Receptor (CASR))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CASR antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 产品特性
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Rabbit polyclonal antibody to Calcium Sensing Receptor (calcium-sensing receptor (hypocalciuric hypercalcemia 1, severe neonatal hyperparathyroidism))
Calcium Sensing Receptor antibody - 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Calcium Sensing Receptor. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product CASR Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: mouse placenta, mouse pancreas, mouse kidney, unboiled TT
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.55 mg/mL
- 缓冲液
- 1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- CASR (Calcium-Sensing Receptor (CASR))
- 别名
- calcium sensing receptor (CASR 产品)
- 别名
- CAR antibody, EIG8 antibody, FHH antibody, FIH antibody, GPRC2A antibody, HHC antibody, HHC1 antibody, HYPOC1 antibody, NSHPT antibody, PCAR1 antibody, CaR antibody, Gprc2a antibody, gprc2a antibody, xV2R F-1 antibody, CASR antibody, calcium sensing receptor antibody, calcium-sensing receptor antibody, calcium-sensing receptor L homeolog antibody, CASR antibody, Casr antibody, casr.L antibody
- 背景
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The protein encoded by this gene is a G protein-coupled receptor that is expressed in the parathyroid hormone (PTH)-producing chief cells of the parathyroid gland, and the cells lining the kidney tubule. It senses small changes in circulating calcium concentration and couples this information to intracellular signaling pathways that modify PTH secretion or renal cation handling, thus this protein plays an essential role in maintaining mineral ion homeostasis. Mutations in this gene cause familial hypocalciuric hypercalcemia, familial, isolated hypoparathyroidism, and neonatal severe primary hyperparathyroidism.
Cellular Localization: Cell membrane - 分子量
- 121 kDa
- 基因ID
- 846
- UniProt
- P41180
- 途径
- Positive Regulation of Peptide Hormone Secretion, Carbohydrate Homeostasis
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