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DLD 抗体

KO Validated DLD 适用: 人 WB, IF, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854985
发货至: 中国
  • 抗原 See all DLD 抗体
    DLD (Dihydrolipoamide Dehydrogenase (DLD))
    适用
    • 44
    • 27
    • 26
    • 8
    • 5
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    宿主
    • 52
    • 6
    克隆类型
    • 50
    • 8
    多克隆
    标记
    • 36
    • 5
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLD antibody is un-conjugated
    应用范围
    • 53
    • 22
    • 21
    • 11
    • 9
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
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    Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit Polyclonal antibody to DLD (dihydrolipoamide dehydrogenase)
    DLD antibody
    纯化方法
    Affinity purified by Protein A.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human DLD. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product DLD Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: Mouse brain , 293T , PC-12 , Rat2 , HeLa

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Shin, Lee, You, Kim, Roh: "Dihydrolipoamide dehydrogenase regulates cystine deprivation-induced ferroptosis in head and neck cancer." in: Redox biology, Vol. 30, pp. 101418, (2020) (PubMed).

  • 抗原
    DLD (Dihydrolipoamide Dehydrogenase (DLD))
    别名
    dihydrolipoamide dehydrogenase (DLD 产品)
    背景
    This gene encodes the L protein of the mitochondrial glycine cleavage system. The L protein, also named dihydrolipoamide dehydrogenase, is also a component of the pyruvate dehydrogenase complex, the alpha-ketoglutarate dehydrogenase complex, and the branched-chain alpha-keto acide dehydrogenase complex. Mutations in this gene have been identified in patients with E3-deficient maple syrup urine disease and lipoamide dehydrogenase deficiency.

    Cellular Localization: Mitochondrion matrix
    分子量
    54 kDa
    基因ID
    1738
    UniProt
    P09622
    途径
    Ribonucleoside Biosynthetic Process, Cell RedoxHomeostasis
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