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Insulin Receptor 抗体 (C-Term)

KO Validated INSR 适用: 人 WB, ICC, IF, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854945
发货至: 中国
  • 抗原 See all Insulin Receptor (INSR) 抗体
    Insulin Receptor (INSR)
    抗原表位
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    C-Term
    适用
    • 169
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    宿主
    • 166
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    克隆类型
    • 158
    • 33
    多克隆
    标记
    • 116
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    This Insulin Receptor antibody is un-conjugated
    应用范围
    • 141
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    Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    人, 小鼠, 大鼠, 斑马鱼
    产品特性
    Rabbit Polyclonal antibody to Insulin Receptor (insulin receptor)
    Insulin Receptor antibody
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the C-terminus region of human Insulin Receptor. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product INSR Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: NIH-3T3 , PC-12 , rat liver

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.31 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Insulin Receptor (INSR)
    别名
    insulin receptor (INSR 产品)
    别名
    CD220 antibody, HHF5 antibody, 4932439J01Rik antibody, D630014A15Rik antibody, IR antibody, IR-A antibody, IR-B antibody, 18402 antibody, CG18402 antibody, DIHR antibody, DILR antibody, DIR antibody, DIRH antibody, DIRbeta antibody, DInR antibody, DInr antibody, Dir-a antibody, Dir-b antibody, Dmel\\CG18402 antibody, INR antibody, INS antibody, Inr antibody, Inr-alpha antibody, Inr-beta antibody, InsR antibody, dINR antibody, dIR antibody, dIRH antibody, dInR antibody, dInr antibody, dInsR antibody, dinr antibody, dir antibody, er10 antibody, inr antibody, insulin/insulin-like growth factor receptor antibody, l(3)05545 antibody, l(3)93Dj antibody, l(3)er10 antibody, lnR antibody, ir-A antibody, CTK-1 antibody, ir antibody, INSR antibody, NV14476 antibody, cd220 antibody, hhf5 antibody, insulin receptor antibody, Insulin-like receptor antibody, insulin receptor L homeolog antibody, INSR antibody, Insr antibody, InR antibody, LOC100122567 antibody, LOC100451802 antibody, insr.L antibody
    背景
    After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. Two transcript variants encoding different isoforms have been found for this gene.

    Cellular Localization: Membrane, Single-pass type I membrane protein
    分子量
    156 kDa
    基因ID
    3643
    UniProt
    P06213
    途径
    NF-kappaB Signaling, RTK signaling, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity
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