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Prosaposin 抗体

KO Validated PSAP 适用: 人 WB, IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2854916
发货至: 中国
  • 抗原 See all Prosaposin (PSAP) 抗体
    Prosaposin (PSAP)
    适用
    • 38
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    宿主
    • 40
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    克隆类型
    • 42
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    多克隆
    标记
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    This Prosaposin antibody is un-conjugated
    应用范围
    • 40
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    交叉反应
    人, 小鼠, 大鼠
    产品特性
    Rabbit polyclonal antibody to PSAP (prosaposin)
    PSAP antibody [N1N3]
    纯化方法
    Purified by antigen-affinity chromatography.
    质量等级
    KO Validated
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PSAP. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PSAP Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: mouse brain , rat brain , HeLa

    Validation: KO/KD

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1.98 mg/mL
    缓冲液
    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Prosaposin (PSAP)
    别名
    prosaposin (PSAP 产品)
    别名
    GLBA antibody, SAP1 antibody, AI037048 antibody, SGP-1 antibody, SGP1A antibody, cb759 antibody, wu:fa14a06 antibody, wu:fb36e02 antibody, wu:fb58g07 antibody, PSAP antibody, PSP-A antibody, SFTPA1B antibody, SP-A antibody, prosaposin antibody, surfactant protein A1 antibody, PSAP antibody, Psap antibody, psap antibody, LOC100011417 antibody, LOC100304726 antibody, LOC100526719 antibody, SFTPA1 antibody
    背景
    This gene encodes a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities. Mutations in this gene have been associated with Gaucher disease, Tay-Sachs disease, and metachromatic leukodystrophy. Alternative splicing results in multiple transcript variants encoding different isoforms.

    Cellular Localization: Lysosome
    分子量
    58 kDa
    基因ID
    5660
    UniProt
    P07602
    途径
    Positive Regulation of Endopeptidase Activity
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